Midwest Brain and Spine, Centerpoint Medical Center, Department of Neurosurgery, Independence, Missouri, USA.
World Neurosurg. 2010 Apr;73(4):285-8. doi: 10.1016/j.wneu.2010.02.042.
The use of "stand-alone" contrast myelography (i.e., without computed tomography) has a proven track record in developing nations where few patients have access to magnetic resonance imaging, whether on the basis of prohibitive cost or the absence of such a modality altogether. To substantiate the author's 12-year experience with more than 300 myelograms performed in 16 different countries (plus some 1500 studies during 30 years of practice in the United States), a prospective pilot study was undertaken over 1 month in a community-based neurosurgical setting in western Kenya. Forty patients underwent cervical or lumbar myelography at Tenwek Hospital under the auspices of the Neurosurgery Training Program for East, Central, and South Africa (NSTP-ECSA) following failure of conservative measures to treat spine-related pathology. Thirty-five of the forty patients (88%) came to definitive surgery on the basis of a positive study that correlated with their clinical history and physical examination. There were no significant complications from the procedures, and no false-positive studies, with virtually all patients returning to normal activity and/or gainful employment within 3 weeks of their surgery. Myelography as a stand-alone diagnostic procedure is a sensitive, specific, and cost-effective means of diagnosing symptomatic degenerative spine disorders. Accordingly, its use should be encouraged at every NSTP-ECSA training site to address such ubiquitous pathology.
“独立”对比脊髓造影(即没有计算机断层扫描)在发展中国家有着可靠的应用记录,这些国家的少数患者能够获得磁共振成像,无论是由于高昂的费用还是完全缺乏这种方式。为了证实作者在 16 个不同国家进行了超过 300 次脊髓造影,以及在美国 30 年的实践中进行了大约 1500 次研究的 12 年经验,在肯尼亚西部的一个社区神经外科环境中进行了为期 1 个月的前瞻性试点研究。在东非、中非和南非神经外科培训计划(NSTP-ECSA)的主持下,40 名患者在 Tenwek 医院接受了颈椎或腰椎脊髓造影,这些患者在经过保守治疗治疗脊柱相关病变失败后接受了治疗。根据与他们的临床病史和体格检查相关的阳性研究,40 名患者中有 35 名(88%)接受了确定性手术。这些手术没有出现重大并发症,也没有假阳性研究,几乎所有患者在手术后 3 周内都恢复了正常活动和/或有收益的工作。作为一种独立的诊断程序,脊髓造影是一种敏感、特异和具有成本效益的诊断症状性退行性脊柱疾病的方法。因此,应该鼓励在每个 NSTP-ECSA 培训地点使用这种方法,以解决这种普遍存在的病理学问题。