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避孕甾体激素在肥胖女性中的代谢和药代动力学:综述。

Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review.

机构信息

Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA.

出版信息

Contraception. 2010 Oct;82(4):314-23. doi: 10.1016/j.contraception.2010.04.016. Epub 2010 May 26.

Abstract

The effect of obesity on drug metabolism and pharmacokinetics is poorly understood, and this is particularly true in regard to contraceptive steroids. This article will review the known and theoretical physiologic and pharmacologic interactions between obesity and contraceptive steroids.

摘要

肥胖对药物代谢和药代动力学的影响尚未完全阐明,这在避孕甾体激素方面尤其如此。本文将回顾肥胖与避孕甾体激素之间已知和理论上的生理和药理相互作用。

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