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[内镜超声检查对胰腺神经内分泌肿瘤诊断的贡献]

[Contribution of endoscopic ultrasonography to the diagnosis of neuroendocrine pancreatic tumors].

作者信息

Díaz Roca Ana Belén, Iglesias-García Julio, Lariño-Noia Jose, Orive Víctor, Domínguez-Muñoz J Enrique

机构信息

Servicio de Aparato Digestivo, Hospital de Basurto, Bilbao, Spain.

出版信息

Gastroenterol Hepatol. 2011 Jan;34(1):29-34. doi: 10.1016/j.gastrohep.2010.05.010. Epub 2010 Sep 19.

Abstract

Neuroendocrine pancreatic tumors (NEPT) are relatively infrequent tumors, with an incidence of approximately 1 case per 100.000 inhabitants, representing only 1-2% of pancreatic neoplasms. Localization and staging of NEPT prior to surgery is essential to allow treatment optimization. However, localizing these tumors is often difficult, mainly because of their small size. On ultrasound, NEPT usually appear as rounded, hypoechoic and homogeneous lesions, with precise limits and peripheral enhancement due to their significant vascularization. The most precise technique for the diagnosis and localization of NEPT is endoscopic ultrasound (EUS), with a sensitivity and specificity as high as 95%, clearly superior to those of other imaging procedures. Overall diagnostic accuracy may even be increased by associating EUS-guided fine-needle aspiration.

摘要

神经内分泌胰腺肿瘤(NEPT)是相对罕见的肿瘤,发病率约为每10万居民中有1例,仅占胰腺肿瘤的1-2%。术前对NEPT进行定位和分期对于优化治疗至关重要。然而,定位这些肿瘤通常很困难,主要是因为它们体积小。在超声检查中,NEPT通常表现为圆形、低回声且均匀的病变,界限清晰,由于其丰富的血管形成而有周边强化。诊断和定位NEPT最精确的技术是内镜超声(EUS),其灵敏度和特异性高达95%,明显优于其他成像检查。通过联合EUS引导下细针穿刺,总体诊断准确性甚至可能提高。

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