双源CT在评估冠状动脉疾病中的临床价值

[Clinical value of dual-source CT in evaluating coronary artery disease].

作者信息

Chen Shao-yuan, Su You-su, Xie Pei-yi, Xu Su-ling, Fang Ye-qing, Huang An-rong

机构信息

Department of Cardiology, Nanshan People's Hospital, Guangdong Medical College, Shenzhen 518052, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2010 Sep;30(9):2125-7.

PMID:20855268

Abstract

OBJECTIVE

To analyze the clinical value of dual-source CT (DSCT) in the diagnosis of coronary artery disease.

METHODS

Fifty-five patients with suspected coronary heart disease underwent both DSCT coronary angiography (DSCTCA) and selective coronary angiography (CAG) examination, and the diagnostic sensitivity, specificity and accuracy of the DSCTCA was evaluated.

RESULTS

The sensitivity, specificity, positive and negative predictive value, and accuracy of DSCT in the diagnosis of coronary heart disease were 97.7%, 72.6%, 93.5%, 88.9% and 92.7% by the number of patients, respectively; by calculating the coronary arteries, the sensitivity, specificity, positive and negative predictive value, accuracy were 94.9%, 95.8%, 92.5%, 97.1%, 95.5%, respectively. According to the lesion segment, these values were 88.2%, 96.9%, 90.5%, 96.1%, 94.7%, respectively. DSCTCA showed no significant difference from CAG for a diagnostic purpose, nor did their vessel sensitivity, specificity, positive and negative predictive value, and accuracy in different coronaries differ significantly.

CONCLUSION

DSCT has a diagnostic accuracy of coronary heart disease close to that CAG and can on some occasion serve as an alternative to CAG in the screening of coronary artery disease.

摘要

目的

分析双源CT（DSCT）在冠心病诊断中的临床价值。

方法

55例疑似冠心病患者同时接受了DSCT冠状动脉造影（DSCTCA）和选择性冠状动脉造影（CAG）检查，并评估了DSCTCA的诊断敏感性、特异性和准确性。

结果

按患者数量计算，DSCT诊断冠心病的敏感性、特异性、阳性和阴性预测值以及准确性分别为97.7%、72.6%、93.5%、88.9%和92.7%；按冠状动脉计算，敏感性、特异性、阳性和阴性预测值、准确性分别为94.9%、95.8%、92.5%、97.1%、95.5%。按病变节段计算，这些值分别为88.2%、96.9%、90.5%、96.1%、94.7%。DSCTCA与CAG在诊断目的上无显著差异，它们在不同冠状动脉中的血管敏感性、特异性、阳性和阴性预测值以及准确性也无显著差异。