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下颌髁突中两种生长调节因子存在的新临床证据:半侧颜面短小畸形下颌骨的半侧下颌骨延长

New clinical-based evidence for the existence of 2 growth regulators in mandibular condyles: hemimandibular elongation in hemifacial microsomia mandible.

作者信息

Obwegeser Hugo L, Obwegeser Joachim A

机构信息

Department of Cranio-Maxillofacial Surgery, University Hospital Zurich, Zurich, Switzerland.

出版信息

J Craniofac Surg. 2010 Sep;21(5):1595-600. doi: 10.1097/SCS.0b013e3181edc547.

Abstract

This is the first description of a secondary mandibular overgrowth due to condylar misregulation in a congenitally undergrown mandible. This case of unilateral hemifacial microsomia proves the postulated existence (Mandibular Growth Anomalies: Terminology, Aetiology, Diagnosis, Treatment, 2001) of 2 different growth regulators in the condyle of each side of the mandible. It shows clear and typical symptoms of hemimandibular hyperplasia on its right side and of hemimandibular elongation on its left mandible despite the existence of a well-developed hemifacial microsomia on the same side. Correction was carried out on the basis of our routine planning and planning principles, including condylectomy on the side of the hemifacial microsomia, because of still active hemimandibular elongation.

摘要

这是首次对先天性下颌发育不全中髁突调节异常导致的继发性下颌过度生长进行的描述。这例单侧半侧颜面短小畸形病例证实了(《下颌生长异常:术语、病因、诊断、治疗》,2001年)下颌骨两侧髁突中存在两种不同生长调节因子的假设。尽管同一侧存在发育良好的半侧颜面短小畸形,但它右侧表现出明显且典型的半侧下颌骨增生症状,左侧下颌骨表现出半侧下颌骨延长症状。基于我们的常规规划和规划原则进行了矫正,包括对存在半侧颜面短小畸形一侧进行髁突切除术,因为半侧下颌骨仍在积极延长。

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