Polyzos Stergios A, Anastasilakis Athanasios D, Iakovou Ioannis P, Partsalidou Valassia
Second Medical Clinic, Ippokration Hospital, Aristotle University of Thessaloniki, Greece.
Arq Bras Endocrinol Metabol. 2010 Aug;54(6):578-82. doi: 10.1590/s0004-27302010000600012.
Co-existence of primary hyperparathyroidism (PHPT) and non-medullary thyroid carcinoma has been previously reported in sporadic case reports and some surgical series, but the majority of cases concerned women with occult papillary carcinomas without cervical lymph node involvement. We present a 71-year man with PHPT and multinodular goiter who was subjected to surgery for single parathyroid adenoma and was found to have synchronous multifocal papillary thyroid carcinoma (PTC) with cervical lymph node involvement. Review of the literature retrieved only a few similar cases. Ultrasonography of both thyroid and parathyroid glands might be considered in patients with hyperparathyroidism. Given that there are no specific guidelines for the management of patients with synchronous PHPT and PTC, they should be managed like the cases of single PTC.
原发性甲状旁腺功能亢进症(PHPT)与非髓样甲状腺癌并存的情况此前已在散发病例报告和一些外科系列研究中有所报道,但大多数病例涉及隐匿性乳头状癌且无颈部淋巴结受累的女性。我们报告一例71岁患有PHPT和多结节性甲状腺肿的男性,因单发甲状旁腺腺瘤接受手术,术中发现同时存在多灶性乳头状甲状腺癌(PTC)并伴有颈部淋巴结受累。文献回顾仅检索到少数类似病例。对于甲状旁腺功能亢进症患者,可考虑对甲状腺和甲状旁腺进行超声检查。鉴于目前尚无针对同步发生的PHPT和PTC患者管理的具体指南,应按照单发PTC病例进行处理。