Wiratkapun Cholatip, Fusuwankaya Ekkapong, Wibulpholprasert Bussanee, Lertsittichai Panuwat
Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University Bangkok, Thailand.
J Med Assoc Thai. 2010 Sep;93(9):1058-64.
To evaluate the diagnostic accuracy of the vacuum-assisted stereotactic core needle biopsy (CNB) for breast lesions.
Sixty-four lesions that had undergone vacuum-assisted stereotactic CNB between January 2003 and December 2005 in Ramathibodi Breast diagnostic center were included in this study. Pathologic results of CNB were reviewed and correlated with pathologic results of subsequent open surgery. For benign lesions without surgery, the authors correlated the result of CNB with stability of the lesion at or more than 2-year interval follow-up. Agreement rate, high-risk under estimate rate, Ductal carcinoma in situ (DCIS) underestimate rate, false negative rate, and sensitivity were accessed
The pathologic results for the CNB were malignancy in 20%, high-risk in 13%, and benign in 67%. The agreement rate was 93.8% (60 of 64). The under estimate rate for atypical ductal hyperplasia (ADH) was 50% (3 of 6). There was no underestimate for DCIS in the present study. Of 43 benign lesions, malignancy was found at subsequent open surgery in one lesion and false negative rate was 6%. Calculated sensitivity was 96%.
Vacuum-assisted CNB is an accurate method for evaluating breast lesions. This procedure is an alternative to surgical excision for lesion assessments.
评估真空辅助立体定向粗针活检(CNB)对乳腺病变的诊断准确性。
本研究纳入了2003年1月至2005年12月期间在拉玛蒂博迪乳腺诊断中心接受真空辅助立体定向CNB的64个病变。回顾了CNB的病理结果,并将其与后续开放手术的病理结果进行关联。对于未进行手术的良性病变,作者将CNB的结果与病变在2年或更长时间间隔随访中的稳定性进行关联。评估一致率、高危低估率、导管原位癌(DCIS)低估率、假阴性率和敏感性。
CNB的病理结果为恶性的占20%,高危的占13%,良性的占67%。一致率为93.8%(64个中的60个)。非典型导管增生(ADH)的低估率为50%(6个中的3个)。本研究中DCIS没有低估情况。在43个良性病变中,后续开放手术发现1个病变为恶性,假阴性率为6%。计算得出的敏感性为96%。
真空辅助CNB是评估乳腺病变的一种准确方法。该程序是病变评估中手术切除的一种替代方法。