[肠系膜下动脉不同结扎方式在乙状结肠癌或直肠癌手术中的作用：一项荟萃分析]
[Role of different ligation of the inferior mesenteric artery in sigmoid colon or rectal cancer surgery: a meta-analysis].
作者信息
Chen Shi-cai, Song Xin-ming, Chen Zhi-hui, Li Ming-zhe, He Yu-long, Zhan Wen-hua
机构信息
Department of Gastrointestinal Surgery and Colorectal Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
出版信息
Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Sep;13(9):674-7.
OBJECTIVE
To evaluate the effect of different ligation of the inferior mesenteric artery in sigmoid colon or rectal cancer surgery on 5-year overall survival rate and operative mortality.
METHODS
The results of several literatures from different countries on high or low ligation of the inferior mesenteric artery and prognosis were analyzed using meta-analysis.
RESULTS
Seven studies were included. The 5-year overall survival rate was compared between low and high ligation. The odd ratio (OR) for 5-year survival was 0.87 (95% CI=0.76-0.98, P=0.02), and the OR for perioperative mortality was 1.28 (95% CI=0.94-1.75, P=0.19).
CONCLUSIONS
High ligation of the inferior mesenteric artery may improve 5-year overall survival rate. Perioperative mortality may not be influenced by the level of ligation.
目的
评估乙状结肠癌或直肠癌手术中不同的肠系膜下动脉结扎方式对5年总生存率和手术死亡率的影响。
方法
采用Meta分析对不同国家的多篇关于肠系膜下动脉高结扎或低结扎与预后的文献结果进行分析。
结果
纳入7项研究。比较了低结扎和高结扎的5年总生存率。5年生存的比值比（OR）为0.87（95%可信区间[CI]=0.76-0.98，P=0.02），围手术期死亡率的OR为1.28（95%CI=0.94-1.75，P=0.19）。
结论
肠系膜下动脉高结扎可能提高5年总生存率。围手术期死亡率可能不受结扎水平的影响。
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