Department of Urogynaecology (affiliated to Melbourne University), Mercy Hospital for Women, Melbourne, Victoria, Australia.
Neurourol Urodyn. 2010 Sep;29(7):1262-6. doi: 10.1002/nau.20862.
To compare the safety and efficacy of midurethral sling surgery for management of urinary stress incontinence in women over 80 years versus younger women.
1225 consecutive women with urodynamic stress incontinence had a synthetic midurethral sling (955 retropubic, 270 transobturator) at our institution between 1999 and 2007. Ninety one percent (n = 1112) of the patients were interviewed via phone call with a structured questionnaire and were included in the analysis. The mean follow-up was 50 ± 24 months (range 12-114). Comparison between elderly (≥80 years, n = 96) and younger patients (<80 years, n = 1016) was performed.
The overall subjective cure rate was 85% (elderly 81%, younger 85%, = 0.32). There was no significant difference in cure rate between retropubic and transobturator sling in the elderly group (82% vs. 79.3%, P = 0.75). The bladder perforation rate was similar between the two groups (3%). The hospitalization time was significantly longer in the elderly (1.6 ± 1.7 days vs. 0.7 ± 1.1 days, P<0.001). However, major perioperative complications were uncommon (1%). Of the patients who had an isolated sling procedure, 37% of the elderly and 9% of the young patients failed their 1st trial of void (P < 0.001). However, the long-term rate of voiding difficulty was similar between the two groups (elderly 8% vs. young 6%, P = 0.21). The rate of de novo urge incontinence was similar between the two groups (7%).
Retropubic and transobturator slings in women older than 80 years are effective and safe but are associated with an increased risk of transient postoperative voiding difficulty.
比较经阴道尿道中段吊带术治疗 80 岁以上女性与年轻女性压力性尿失禁的安全性和疗效。
1999 年至 2007 年,我们机构对 1225 例压力性尿失禁患者进行了经阴道尿道中段吊带术(955 例耻骨后,270 例经闭孔)。对 1112 例(91%)患者通过电话进行了结构化问卷调查,并进行了分析。平均随访时间为 50±24 个月(范围 12-114)。比较了老年组(≥80 岁,n=96)和年轻组(<80 岁,n=1016)。
总体主观治愈率为 85%(老年组 81%,年轻组 85%,P=0.32)。老年组耻骨后和经闭孔吊带的治愈率无显著差异(82%比 79.3%,P=0.75)。两组膀胱穿孔率相似(3%)。老年组住院时间明显较长(1.6±1.7 天比 0.7±1.1 天,P<0.001)。然而,围手术期重大并发症并不常见(1%)。在仅行吊带术的患者中,37%的老年患者和 9%的年轻患者首次排尿失败(P<0.001)。然而,两组长期排尿困难的发生率相似(老年组 8%比年轻组 6%,P=0.21)。两组新发急迫性尿失禁发生率相似(7%)。
80 岁以上女性的耻骨后和经闭孔吊带术有效且安全,但术后短期排尿困难风险增加。