卵黄囊是否是早孕染色体异常的新标志物？
Is the yolk sac a new marker for chromosomal abnormalities in early pregnancy?
机构信息
Department of Gynecology and Obstetrics, University of Heidelberg, Heidelberg, Germany.
出版信息
Arch Gynecol Obstet. 2011 Mar;283 Suppl 1:23-6. doi: 10.1007/s00404-010-1696-6. Epub 2010 Sep 30.
INTRODUCTION
Abnormal yolk sac size is associated with fetal miscarriage. This is a case report of two pregnancies with abnormal yolk sacs.
MATERIALS AND METHODS
In one case, a twofold sac was found; in the other case, the yolk sac was not of spherical form.
CONCLUSION
Currently available publications demonstrate a correlation between abnormal yolk sac size and miscarriage. However, in both cases a trisomy was confirmed. It should therefore be discussed whether form and size of the yolk sac could be a marker for chromosomal abnormalities of the fetus.
介绍
卵黄囊大小异常与胎儿流产有关。本病例报告了两例卵黄囊异常的妊娠。
材料和方法
一例发现双胎妊娠囊，另一例卵黄囊不是球形。
结论
目前的文献表明卵黄囊大小异常与流产有关。然而，在这两种情况下都证实存在三体。因此，应该讨论卵黄囊的形态和大小是否可以作为胎儿染色体异常的标志物。
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