磁共振成像在（深部浸润型）子宫内膜异位症评估中的应用：弥散加权成像的价值。

Magnetic resonance imaging in the evaluation of (deep infiltrating) endometriosis: the value of diffusion-weighted imaging.

机构信息

Department of Radiology, Endometriosis Center VUMC, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

J Magn Reson Imaging. 2010 Oct;32(4):1003-9. doi: 10.1002/jmri.22310.

DOI:10.1002/jmri.22310

PMID:20882634

Abstract

PURPOSE

To assess the value of magnetic resonance (MR)diffusion-weighted imaging (DWI) in the evaluation of deep infiltrating endometriosis (DIE).

MATERIALS AND METHODS

In a prospective single-center study, DWI was added to the standard MRI protocol in 56 consecutive patients with known or suspected endometriosis. Endometriotic lesions as well as (functional) ovarian cysts were analyzed for location, size, and signal intensity on T1, T2, and DWI. Apparent diffusion coefficient (ADC) values were calculated using b-values of 50, 400, 800,and 1200 s/mm(2). Statistical analysis included the Spearman correlation coefficient, Mann-Whitney U, and Kruskal-Wallis tests.

RESULTS

A total of 110 lesions (62 endometrial cysts and 48 DIE) were detected, 60 of which were large enough to analyze. Mean ADC values of endometrial cysts and functional ovarian cysts were 1.10 x 10(-3)/mm(2)/s and 2.14 x 10(-3)/mm(2)/s, respectively. Mean ADC values of DIE retrocervical, infiltrating the colon, and bladder were 0.70 x 10(-3)/mm(2)/s, 0.77 x 10(-3)/mm(2)/s, and 0.79 x 10(-3)/mm(2)/s, respectively. ADC values of DIE did not show a significant difference between varying pelvic locations (P = 0.63).

CONCLUSION

Results of our study suggest that ADC values of DIE are consistently low, without significant difference between pelvic locations.

摘要

目的

评估磁共振（MR）弥散加权成像（DWI）在评估深部浸润性子宫内膜异位症（DIE）中的价值。

材料与方法

在一项前瞻性单中心研究中，对 56 例已知或疑似患有子宫内膜异位症的患者在标准 MRI 方案中添加了 DWI。对子宫内膜异位症病变以及（功能性）卵巢囊肿进行了位置、大小和 T1、T2 和 DWI 信号强度分析。使用 b 值为 50、400、800 和 1200 s/mm2 计算表观弥散系数（ADC）值。统计分析包括 Spearman 相关系数、Mann-Whitney U 和 Kruskal-Wallis 检验。

结果

共检测到 110 个病变（62 个子宫内膜囊肿和 48 个 DIE），其中 60 个足够大可以进行分析。子宫内膜囊肿和功能性卵巢囊肿的平均 ADC 值分别为 1.10×10-3/mm2/s 和 2.14×10-3/mm2/s。DIE 宫颈后、浸润结肠和膀胱的平均 ADC 值分别为 0.70×10-3/mm2/s、0.77×10-3/mm2/s 和 0.79×10-3/mm2/s。DIE 的 ADC 值在不同的盆腔位置之间没有显著差异（P=0.63）。