Arrhythmia Service, University of Western Ontario, London, Ontario, Canada.
Heart Rhythm. 2011 Jan;8(1):16-22. doi: 10.1016/j.hrthm.2010.09.069. Epub 2010 Sep 25.
Complete circumferential antral ablation may not be necessary for successful pulmonary vein (PV) isolation in patients with paroxysmal atrial fibrillation (AF).
We examined the feasibility of a noncircumferential approach limited to segments of the antra required for PV-atrial conduction.
During ablation for paroxysmal AF, each PV antrum was divided into six segments, and ablation was sequentially targeted to antral segments with the earliest activity until bidirectional isolation was achieved. Ablation at the ostium was avoided. Patients requiring complete circumferential ablation (circumferential group) were compared with those undergoing incomplete antral ablation (noncircumferential group) with respect to freedom from symptomatic atrial arrhythmia, procedure, and ablation times.
Ninety-nine patients underwent ablation with successful isolation of PVs (n = 37 circumferential; n = 62 noncircumferential). There were no significant differences in age, gender, AF duration, or LA size. Procedure time (202 ± 45 vs. 185 ± 47 minutes; P = .06) and ablation time (51 ± 15 vs. 41 ± 14 minutes; P = .004) were shorter in the noncircumferential group. During follow-up (12 ± 6 months), freedom from symptomatic recurrence was 73% in both groups (P = .97), with organized atrial tachycardia being more common in the circumferential group (P = .06). In 22 patients undergoing repeat study, PV reconnection was demonstrated in 82% and 81% of PVs in each group. Reconnection in the noncircumferential group occurred in previously ablated segments in 10 (77%) of 13 cases.
Noncircumferential antral ablation achieves similar success rates with shorter procedure and ablation times than circumferential ablation. Greater attention should be focused on producing permanent lesions rather than on completing antral encirclement after isolation is achieved.
对于阵发性心房颤动(AF)患者,完全环形肺静脉(PV)隔离可能并非必需。
我们检查了一种非环形方法的可行性,该方法仅限于需要 PV-心房传导的窦房结段。
在阵发性 AF 的消融过程中,每个 PV 窦房结分为六个节段,并且顺序靶向具有最早活动的窦房结段,直到实现双向隔离。避免在窦口进行消融。将需要完全环形消融(环形组)的患者与进行不完全窦房结消融(非环形组)的患者进行比较,比较内容为无症状性心房心律失常的发生率、手术过程和消融时间。
99 例患者接受了消融术,成功地隔离了 PV(n = 37 例环形;n = 62 例非环形)。两组患者在年龄、性别、AF 持续时间或 LA 大小方面无显著差异。非环形组的手术时间(202 ± 45 分钟对 185 ± 47 分钟;P =.06)和消融时间(51 ± 15 分钟对 41 ± 14 分钟;P =.004)较短。在随访(12 ± 6 个月)期间,两组的无症状复发率均为 73%(P =.97),环形组更常见的是有组织的房性心动过速(P =.06)。在 22 例接受重复研究的患者中,两组各有 82%(13 例中的 10 例)和 81%(13 例中的 10 例)的 PV 重新连接。在非环形组中,10 例(77%)中的 13 例中,再连接发生在以前消融的节段。
非环形窦房结消融术与环形消融术相比,具有相似的成功率,且手术和消融时间更短。在实现隔离后,应更加关注产生永久性病变,而不是完成窦房结环周消融。