实验性硝酸铅中毒：丁鱥（Tinca tinca, L.）鳃的微观和超微结构研究

Roncero V, Vincente J A, Redondo E, Gãzquez A, Duran E

Department of Histology and Pathological Anatomy, Faculty of Veterinary Sciences, Caceres, Spain.

Environ Health Perspect. 1990 Nov;89:137-44. doi: 10.1289/ehp.9089137.

A microscopic, ultrastructural, and morphometric study was made of the gills of tench (Tinca tinca, L.) subjected to acute experimental lead nitrate poisoning. Twenty-one adult tench were subjected to poisoning and a further 22 were used as controls. Lesions were characterized by the appearance of edema and epithelial hyperplasia and necrosis, both in cells forming part of the filtration barrier and in those in the interlamellar space. These processes developed in the course of the experiment, leading to the death of tench after 12 to 15 days of exposure to 75 ppm lead nitrate, at which point the concentrations of lead in the gills had reached their maximum.

对遭受急性实验性硝酸铅中毒的丁鱥（Tinca tinca, L.）鳃进行了微观、超微结构和形态计量学研究。21条成年丁鱥遭受中毒，另外22条用作对照。病变特征为形成滤过屏障的细胞以及片层间隙中的细胞出现水肿、上皮增生和坏死。这些过程在实验过程中发展，导致丁鱥在暴露于75 ppm硝酸铅12至15天后死亡，此时鳃中铅的浓度达到最高。