Division of Cardiology, Catholic University of Daegu, Daegu, Republic of Korea.
J Cardiol. 2010 Nov;56(3):348-53. doi: 10.1016/j.jjcc.2010.07.006.
Radiofrequency catheter ablation of the cavotricuspid isthmus (CTI) is effective in the treatment of typical atrial flutter (AFL) and atrial fibrillation (AF). AF and AFL often coexist. However, AF often occurs following successful ablation of CTI. The aim of this study was to investigate the predictors of concomitant AF following successful ablation of AFL.
We enrolled 122 patients [59.1 ± 11.3 years, male 100 (82.0%)] with typical AFL, who received successful ablation of the CTI. They were followed up at outpatient clinic (24.6 ± 25.7 months). Twelve-lead electrocardiogram and Holter monitoring were used to confirm the diagnosis of recurrent AFL or AF. We assessed prior history of AF, structural heart disease, left ventricular ejection fraction, left atrial diameter (LAD), left atrial volume index (LAVI), and AFL cycle length.
Among the 122 ablated patients, 15 (12.3%) had recurrent AFL and 33 (27.0%) had recurrent AF. In univariate logistic analysis, LAD and LAVI could significantly predict the recurrence of AF after AFL ablation. However, multivariate logistic regression analysis found that the independent predictor of recurrent AF was LAVI. An LAVI of 42.6 mL may allow for the differentiation between only AFL and AFL with concomitant AF with 69.0% sensitivity and 69.8% specificity.
LAVI might be a useful predictor for occurrence of AF after ablation of typical AFL.
射频导管消融三尖瓣峡部(CTI)在治疗典型的房扑(AFL)和心房颤动(AF)中是有效的。AF 和 AFL 常同时存在。然而,在 CTI 消融成功后常发生 AF。本研究旨在探讨成功消融 AFL 后并发 AF 的预测因素。
我们招募了 122 名[59.1±11.3 岁,男性 100 名(82.0%)]有典型 AFL 的患者,他们接受了 CTI 的成功消融。在门诊进行随访(24.6±25.7 个月)。12 导联心电图和动态心电图监测用于确认复发 AFL 或 AF 的诊断。我们评估了 AF 的既往史、结构性心脏病、左心室射血分数、左心房直径(LAD)、左心房容积指数(LAVI)和 AFL 周期长度。
在 122 名消融患者中,15 名(12.3%)有复发 AFL,33 名(27.0%)有复发 AF。在单因素逻辑回归分析中,LAD 和 LAVI 可显著预测 AFL 消融后 AF 的复发。然而,多因素逻辑回归分析发现,LAVI 是 AF 复发的独立预测因素。LAVI 为 42.6 mL 可能使仅 AFL 与 AFL 并发 AF 得以区分,其灵敏度为 69.0%,特异性为 69.8%。
LAVI 可能是 AFL 消融后发生 AF 的有用预测指标。