Suppr超能文献

区域麻醉和抗血栓药物:欧洲麻醉学会的建议。

Regional anaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology.

机构信息

Department of Anaesthesiology, Intensive Care and Pain Therapy, Harlaching Hospital, Municipal Hospitals of Munich, Munich, Germany.

出版信息

Eur J Anaesthesiol. 2010 Dec;27(12):999-1015. doi: 10.1097/EJA.0b013e32833f6f6f.

Abstract

BACKGROUND AND OBJECTIVES

performing neuraxial anaesthesia in patients receiving antithrombotic drugs is controversial due to the increased risk of spinal epidural haematoma. Strict adherence to the recommended time intervals between the administration of anticoagulants, neuraxial blockade and the removal of catheters is thought to improve patient safety and reduce the risk of haematoma. Appropriate guidelines have been prepared by a number of national societies of anaesthesiologists, but they do not have universal acceptance. The introduction of new anticoagulants together with recent reports of stent thrombosis in patients with perioperative cessation of antiplatelet drugs have considerably broadened the issue and made revision necessary. To overcome deficiencies in content and applicability, the European Society of Anaesthesiology has taken the initiative to provide current and comprehensive guidelines for the continent as a whole.

METHODS

extensive review of the literature.

RESULTS AND CONCLUSIONS

in order to minimise bleeding complications during regional anaesthetic techniques, care should be taken to avoid traumatic puncture. If a bloody tap occurs when intraoperative anticoagulation is planned, postponing surgery should be considered. Alternatively, catheters can be placed the night before surgery. Regional anaesthesia in patients receiving full anticoagulation treatment continues to be contraindicated. Catheter manipulation and removal carry similar risks to insertion and the same criteria should apply. Appropriate neurological monitoring is essential during the postoperative recovery period and following catheter removal. The final decision to perform regional anaesthesia in patients receiving drugs that affect haemostasis has to be taken after careful assessment of individual risks and benefits.

摘要

背景与目的

由于接受抗血栓药物治疗的患者发生脊柱-硬膜外血肿的风险增加,在这些患者中进行椎管内麻醉存在争议。严格遵循抗凝药物、椎管内阻滞和导管拔出之间建议的时间间隔,被认为可以提高患者安全性,降低血肿风险。一些国家的麻醉师协会已经制定了适当的指南,但这些指南并未被普遍接受。新型抗凝药物的出现,加上最近报告的抗血小板药物围手术期停药后支架血栓形成的情况,大大拓宽了这个问题的范围,使得指南的修订变得必要。为了克服内容和适用性方面的不足,欧洲麻醉学会主动为整个欧洲大陆提供了当前和全面的指南。

方法

对文献进行广泛的回顾。

结果与结论

为了最大限度地减少局部麻醉技术过程中的出血并发症,应注意避免穿刺损伤。如果在计划术中抗凝时出现血性穿刺,应考虑推迟手术。或者,可以在前一天晚上放置导管。接受充分抗凝治疗的患者继续禁忌进行区域麻醉。导管的操作和拔出与插入具有相似的风险,应适用相同的标准。在术后恢复期间和导管拔出后,应进行适当的神经学监测。在仔细评估个体风险和获益后,才能最终决定是否对接受影响止血药物治疗的患者实施区域麻醉。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验