Clinic for Psychiatry and Psychotherapy II, Ulm University, Department of Psychotherapeutic Medicine and Psychosomatics, Bezirkskrankenhaus Günzburg, Germany.
Psychiatry Res. 2010 Dec 30;184(3):196-200. doi: 10.1016/j.pscychresns.2010.03.009.
The prevalence of arachnoid cysts (AC) is considerably increased in psychiatric patients, suggesting a possible causal relationship between AC and certain psychiatric disorders. Neurosurgery of AC in psychiatric disorders is, however, not recommended if no accompanying neurological symptoms or signs of increased intracranial pressure are present. In two cases of slow onset personality disorder in persons suffering from so-called asymptomatic AC, we performed AC neurosurgery beyond established rules. Both comparisons before and after neurosurgery of psychopathology and the following long-term course support in retrospect that both cases might be re-diagnosed as having suffered from 'minor' organic personality disorders before AC neurosurgery, which improved thereafter. The two cases did not initially appear to fulfill the established criteria for organic personality disorders either according to ICD-10 or DSM-IV, but in retrospect satisfied most criteria. In themselves, the personality disorders appeared not very severe, but had considerable relevance for the patients' lives. The established rules for AC neurosurgery should be reconsidered at least when therapy-resistant psychiatric disorders are observed in AC sufferers.
蛛网膜囊肿(AC)在精神科患者中的发病率明显增高,这表明 AC 与某些精神疾病之间可能存在因果关系。然而,如果没有伴随神经症状或颅内压升高的迹象,不建议对精神疾病中的 AC 进行神经外科手术。在两名患有所谓无症状 AC 的缓慢起病人格障碍患者中,我们超出既定规则进行了 AC 神经外科手术。神经外科手术前后的精神病理学比较以及随后的长期病程回顾支持这样一种观点,即这两种情况可能在 AC 神经外科手术前被重新诊断为患有“轻微”器质性人格障碍,此后有所改善。根据 ICD-10 或 DSM-IV,这两个病例最初似乎都不符合器质性人格障碍的既定标准,但回顾起来,它们符合大多数标准。这些人格障碍本身似乎并不十分严重,但对患者的生活有很大影响。至少在观察到 AC 患者出现治疗抵抗性精神障碍时,应重新考虑 AC 神经外科手术的既定规则。