犬的精原细胞瘤伴神经上皮分化和支持细胞瘤。
Spermatocytic seminoma with neuroectodermal differentiation and sertoli cell tumor in a dog.
机构信息
Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
出版信息
Vet Pathol. 2011 Sep;48(5):1024-8. doi: 10.1177/0300985810385150. Epub 2010 Oct 7.
Two distinct nodules developed in a cryptorchid testis of an 8-year-old male West Highland White Terrier. One nodule was a Sertoli cell tumor. The other was a spermatocytic seminoma with focal primitive neuroectodermal differentiation: formation of Homer-Wright rosettes and perivascular pseudorosettes, with immunoreactivity for S-100 protein, neuron-specific enolase, synaptophysin, neurofilament-68 kDa, microtubule-associated protein 2, and vimentin. The dog was alive and healthy 2 years after castration.
一只 8 岁雄性威尔斯梗的隐睾睾丸中出现了两个不同的结节。一个结节是支持细胞瘤。另一个是精原细胞瘤伴局灶性原始神经外胚层分化：形成 Homer-Wright 玫瑰花结和血管周围假玫瑰花结，免疫组化染色显示 S-100 蛋白、神经元特异性烯醇化酶、突触素、神经丝-68kDa、微管相关蛋白 2 和波形蛋白阳性。阉割后 2 年，这只狗仍然健康存活。
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