合成离子通道协同作用增强抗菌活性。
Enhancement of antimicrobial activity by synthetic ion channel synergy.
机构信息
Department of Chemistry & Biochemistry, Center for Nanoscience, University of Missouri-Saint Louis, Saint Louis, MO 63121, USA.
出版信息
Chem Commun (Camb). 2010 Nov 21;46(43):8166-7. doi: 10.1039/c0cc03138k. Epub 2010 Oct 8.
PMID:20931142
Abstract
Hydraphile synthetic ion channels were found to enhance the cytotoxicity to E. coli and B. subtilis of erythromycin, kanamycin, rifampicin, and tetracycline when co-administered with the antibiotic at sublethal concentrations of channel.
摘要
水凝胶合成离子通道被发现与抗生素联合使用时，在亚致死浓度的通道下，可增强红霉素、卡那霉素、利福平、四环素对大肠杆菌和枯草芽孢杆菌的细胞毒性。
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