Skowron C, Raoulx M, Skowron F
Centre hospitalier de Valence, France.
Ann Dermatol Venereol. 2010 Oct;137(10):622-5. doi: 10.1016/j.annder.2010.06.025. Epub 2010 Aug 26.
Treatment of anogenital warts (AW) in children and infants is painful because of the destructive techniques involved, as a result of which general anaesthesia may be required. For adults, topical imiquimod is an efficient and well-tolerated product used for these lesions. Here, we report a case demonstrating the benefits of topical imiquimod in the treatment of AW in infant.
A ten-month-old infant was presenting large AW in the inguinal and perianal folds for a period of two months, which persisted despite one month of treatment with podophyllotoxin. After a month of daily application of imiquimod, the AW was completely cured, with no recurrence at six months.
In the literature, we found four similar case reports concerning the efficacy and safety of topical imiquimod for AW in infants. Although topical imiquimod is not licensed for paediatric use, these case reports highlight the benefits of this approach in infants.
由于所涉及的破坏性技术,儿童和婴儿的肛门生殖器疣(AW)治疗很痛苦,因此可能需要全身麻醉。对于成年人,局部用咪喹莫特是用于这些病变的一种有效且耐受性良好的产品。在此,我们报告一例病例,展示了局部用咪喹莫特治疗婴儿AW的益处。
一名10个月大的婴儿腹股沟和肛周皱襞处出现大量AW达两个月,尽管用鬼臼毒素治疗了一个月仍持续存在。在每日应用咪喹莫特一个月后,AW完全治愈,六个月时无复发。
在文献中,我们发现了四份关于局部用咪喹莫特治疗婴儿AW的疗效和安全性的类似病例报告。尽管局部用咪喹莫特未获儿科使用许可,但这些病例报告突出了这种方法在婴儿中的益处。