FliZ 诱导鞭毛基因表达的动力学开关。
FliZ induces a kinetic switch in flagellar gene expression.
机构信息
Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
出版信息
J Bacteriol. 2010 Dec;192(24):6477-81. doi: 10.1128/JB.00751-10. Epub 2010 Oct 8.
Abstract
FliZ is an activator of class 2 flagellar gene expression in Salmonella enterica. To understand its role in flagellar assembly, we investigated how FliZ affects gene expression dynamics. We demonstrate that FliZ participates in a positive-feedback loop that induces a kinetic switch in class 2 gene expression.
摘要
FliZ 是沙门氏菌中 2 类鞭毛基因表达的激活蛋白。为了理解其在鞭毛组装中的作用，我们研究了 FliZ 如何影响基因表达动力学。我们证明 FliZ 参与了一个正反馈回路，该回路诱导 2 类基因表达的动力学开关。
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