慢性免疫介导性神经病的治疗：慢性炎症性脱髓鞘性多发神经根神经病、多灶性运动神经病和 Lewis-Sumner 综合征。

Treatment of chronic immune-mediated neuropathies: chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy, and the Lewis-Sumner syndrome.

机构信息

Department of Pharmacy Services, Department of Pharmacotherapy, University of Utah College of Pharmacy, University of Utah Hospital, Salt Lake City, Utah.

出版信息

Semin Neurol. 2010 Sep;30(4):443-56. doi: 10.1055/s-0030-1267289. Epub 2010 Oct 12.

DOI:10.1055/s-0030-1267289

PMID:20941678

Abstract

Current treatment approaches for the management of chronic immune-mediated peripheral neuropathies are reviewed, including chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN), and the Lewis-Sumner syndrome (LSS). A summary of existing evidence for commonly used treatment modalities, such as corticosteroids, intravenous immune globulin (IVIG), and plasma exchange is provided. Evidence for the use of additional immunosuppressant and immunomodulatory agents is also reviewed.

摘要

现对慢性免疫介导性周围神经病的治疗方法进行综述，包括慢性炎症性脱髓鞘性多发性神经病（CIDP）、多灶性运动神经病（MMN）和 Lewis-Sumner 综合征（LSS）。本文提供了现有常用治疗方法（如皮质类固醇、静脉注射免疫球蛋白[IVIG]和血浆置换）的证据总结。此外，还对其他免疫抑制剂和免疫调节剂的应用证据进行了综述。