Engelhardt H, Paul A, Niebel W, Dechêne A, Przyborek M, Tsagakis K, Kühl H, Jakob H, Erbel R, Eggebrecht H
Klinik für Kardiologie, Westdeutsches Herzzentrum, Universitätsklinikum Essen.
Dtsch Med Wochenschr. 2010 Oct;135(42):2076-80. doi: 10.1055/s-0030-1267486. Epub 2010 Oct 12.
HISTORY AND CLINICAL SYMPTOMS: A 58-year-old man was admitted to our hospital with acute chest pain and subfebrile temperatures. Two years ago, endovascular aortic stent-graft placement had been performed for acute type B aortic dissection complicated by malperfusion syndrome.
CT angiography showed a discrete soft-tissue attenuation mass between the aorta and esophagus. The patient developed progressive swallow disorder and esophago-gastro-duodenoscopy demonstrated deep esophageal ulcerations at the level of the implanted aortic stent-graft. Intravenous treatment with broad spectrum antibiotics was started. The FDG-PET/CT scan showed increased FDG uptake and air entrapment in the affected region establishing the diagnosis of aortoesophageal fistula formation.
Given the generally poor condition of the patient and the high risk of any aggressive surgical intervention, a new limited surgical approach was chosen consisting of open transthoracic esophageal resection, blind closure of the stomach and cervical esophagostomy. A percutaneous endoscopic gastrostomy tube was placed. After three months, esophageal continuity was restored by retrosternal colon interposition. The presented therapeutic management resulted in a full recovery of the patient.
Aortoesophageal fistula is a rare complication of thoracic aortic stent-graft placement. Patient may present with unspecific symptoms such as fever and rised inflammatory markers, but may also present with massive upper gastrointestinal bleeding. The herein presented limited therapy with esophageal resection represents a promising to the otherwise difficult therapy of aortoesophageal fistula.
病史及临床症状:一名58岁男性因急性胸痛和低热入院。两年前,因急性B型主动脉夹层并发灌注不良综合征行血管腔内主动脉支架植入术。
CT血管造影显示主动脉与食管之间有一离散的软组织密度肿块。患者出现进行性吞咽障碍,食管胃十二指肠镜检查显示植入主动脉支架处食管有深部溃疡。开始静脉使用广谱抗生素治疗。FDG-PET/CT扫描显示病变区域FDG摄取增加且有气体潴留,确诊为主动脉食管瘘形成。
鉴于患者一般状况较差且任何积极手术干预风险高,选择了一种新的有限手术方法,包括开胸经胸食管切除术、胃盲端闭合术和颈段食管造口术。放置了经皮内镜下胃造瘘管。三个月后,通过胸骨后结肠间置术恢复食管连续性。所采用的治疗方法使患者完全康复。
主动脉食管瘘是胸主动脉支架植入术的一种罕见并发症。患者可能表现为发热和炎症指标升高等非特异性症状,但也可能出现大量上消化道出血。本文介绍的食管切除有限治疗方法为主动脉食管瘘这种原本治疗困难的疾病提供了一种有前景的治疗方式。