Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
Cardiovasc Intervent Radiol. 2011 Dec;34(6):1182-9. doi: 10.1007/s00270-010-9992-x. Epub 2010 Oct 14.
To assess the accuracy of maximum diameter measurements of aortic aneurysms after endovascular aneurysm repair (EVAR) on axial computed tomographic (CT) images in comparison to maximum diameter measurements perpendicular to the intravascular centerline for follow-up by using three-dimensional (3D) volume measurements as the reference standard.
Forty-nine consecutive patients (73 ± 7.5 years, range 51-88 years), who underwent EVAR of an infrarenal aortic aneurysm were retrospectively included. Two blinded readers twice independently measured the maximum aneurysm diameter on axial CT images performed at discharge, and at 1 and 2 years after intervention. The maximum diameter perpendicular to the centerline was automatically measured. Volumes of the aortic aneurysms were calculated by dedicated semiautomated 3D segmentation software (3surgery, 3mensio, the Netherlands). Changes in diameter of 0.5 cm and in volume of 10% were considered clinically significant. Intra- and interobserver agreements were calculated by intraclass correlations (ICC) in a random effects analysis of variance. The two unidimensional measurement methods were correlated to the reference standard.
Intra- and interobserver agreements for maximum aneurysm diameter measurements were excellent (ICC = 0.98 and ICC = 0.96, respectively). There was an excellent correlation between maximum aneurysm diameters measured on axial CT images and 3D volume measurements (r = 0.93, P < 0.001) as well as between maximum diameter measurements perpendicular to the centerline and 3D volume measurements (r = 0.93, P < 0.001).
Measurements of maximum aneurysm diameters on axial CT images are an accurate, reliable, and robust method for follow-up after EVAR and can be used in daily routine.
通过使用三维(3D)体积测量作为参考标准,评估血管内动脉瘤修复(EVAR)后轴向计算机断层扫描(CT)图像上主动脉瘤最大直径测量与垂直于血管内中心线的最大直径测量在随访中的准确性。
回顾性纳入 49 例连续患者(73 ± 7.5 岁,范围 51-88 岁),这些患者接受了腹主动脉瘤的 EVAR。两名盲法读者两次独立测量了出院时、干预后 1 年和 2 年时的轴向 CT 图像上的最大动脉瘤直径。自动测量垂直于中心线的最大直径。使用专用半自动 3D 分割软件(3surgery、3mensio、荷兰)计算主动脉瘤的体积。直径变化 0.5cm 和体积变化 10%被认为具有临床意义。通过随机效应方差分析的组内相关系数(ICC)计算了观察者内和观察者间的一致性。两种二维测量方法与参考标准相关。
最大动脉瘤直径测量的观察者内和观察者间一致性均为优秀(ICC = 0.98 和 ICC = 0.96)。轴向 CT 图像上测量的最大动脉瘤直径与 3D 体积测量之间存在极好的相关性(r = 0.93,P <0.001),垂直于中心线的最大直径测量与 3D 体积测量之间也存在极好的相关性(r = 0.93,P <0.001)。
轴向 CT 图像上测量最大动脉瘤直径是 EVAR 后随访的一种准确、可靠且稳健的方法,可以在日常工作中使用。