Division of Urology, Department of Surgery, Saint Louis University Medical Center, St. Louis, MO 63104, USA.
Urology. 2011 May;77(5):1217-9. doi: 10.1016/j.urology.2010.06.047. Epub 2010 Oct 13.
Dextranomer/hyaluronic acid (Dx/HA) copolymer (Deflux) subureteral injection has become a widely accepted form of treatment for vesicoureteral reflux. Long-term histologic studies, both experimental and clinical, have supported and proven the occurrence of calcification at the site of previous injection. These calcifications in clinical settings may be perceived as ureteral stones. We report a case of an adolescent female with unresolved right-sided abdominal pain with a past surgical history of Deflux injection, who presented with a distal ureteral calcification. Upon further investigation the calcification was found to be confined to the submural portion rather than the intraluminal ureter.
葡聚糖/透明质酸(Dx/HA)共聚物(Deflux)输尿管下注射已成为治疗膀胱输尿管反流的广泛接受的形式。长期的组织学研究,包括实验和临床研究,都支持并证实了先前注射部位发生钙化的情况。在临床环境中,这些钙化可能被视为输尿管结石。我们报告了一例患有未解决的右侧腹痛的青少年女性,其既往有 Deflux 注射的手术史,其表现为远端输尿管钙化。进一步的研究发现,钙化局限于黏膜下层,而不是腔内输尿管。