A comparative microanatomical study on cross-sections of superficial branch of radial nerve in proximal and distal parts of the forearm: a cadaveric study.

PURPOSE OF STUDY

Changes in peripheral nerve anatomy with age may be the cause for poor prognosis after nerve repair in elderly cases. The aim of the present study is to find out and compare the cross-sectional microanatomy as well as age-related changes in the non-fascicular components of superficial branch of radial nerve at cubital fossa (SBRN-1) and above wrist (SBRN-2).

METHODS

Thirty-eight fresh human (14 male and five female) cadaveric SBRN-1 and SBRN-2 were collected from both sides of 19 cadavers and study has been performed at different magnifications after routine histological (Masson's trichrome stain) processing was done for morphometric analysis (total cross-sectional area [Asc], fascicular area [Af], non-Af [Anonf], adipose [FAT] area and non-adipose area [nFAT]).

RESULTS

SBRN-1 and SBRN-2 belonged to polyfascicular type and showed difference in amount of connective and adipose tissues in Anonf. The number of fascicles in SBRN-1 ranged from 2 to 6 (3.66±0.21, mean±SEM) and in SBRN-2 ranged from 7.5 to 11.5 (9.24±0.26). On comparing the percentage level of adipose tissue (FAT) in total cross-section area (Asc) and in Anonf of SBRN-1 and SBRN-2, the level of adipose tissue was increased with age.

CONCLUSIONS

The amount of adipose tissue in SBRN-1 and SBRN-2 Anonf was found to be high in most of the elderly cases. On comparison, there was not much difference between SBRN-1 and SBRN-2, but, the fascicle count was found to be increasing gradually from proximal to distal part of the SBRN.