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下颌骨 B 细胞淋巴瘤。

B-cell lymphoma of the mandible.

机构信息

Service ORL et chirurgie cervicofaciale, CHU Habib Bourguiba, 3029 Sfax, Tunisia.

出版信息

Eur Ann Otorhinolaryngol Head Neck Dis. 2010 Nov;127(5):186-8. doi: 10.1016/j.anorl.2010.07.009. Epub 2010 Oct 16.

Abstract

INTRODUCTION

Primary malignant lymphoma of the mandible is rare. It is frequently mistaken for a dental lesion, delaying diagnosis. We here report a case of mandibular lymphoma and present the clinical and radiological characteristics and means of treatment of this pathology.

CASE REPORT

A 17-year-old woman consulted for right facial tumefaction with 1 year's evolution. Clinical examination found a mass facing the horizontal branch of the mandible, extending to the right parotid region without cutaneous involvement. CT and MRI showed a large expansive process of mandibular origin with parotid, temporal and intracranial extension. Biopsy indicated large B-cell lymphoma. The patient showed good evolution 2 years after chemotherapy.

CONCLUSION

Lymphoma is the second most frequent form of head and neck tumor, after epidermoid carcinoma. Only 0.6% of locations are mandibular, almost always consisting of B-cell lymphoma. They are often initially misdiagnosed as a dental pathology. Complete remission after chemotherapy ranges from 60 to 80% at 1 year.

摘要

简介

下颌骨原发性恶性淋巴瘤较为罕见。它常被误诊为牙科病变,导致诊断延误。我们在此报告一例下颌骨淋巴瘤病例,并介绍该病理学的临床和影像学特征及治疗方法。

病例报告

一名 17 岁女性因右面部肿胀 1 年就诊。临床检查发现下颌水平支有一肿块,延伸至右侧腮腺区,无皮肤受累。CT 和 MRI 显示下颌骨起源的大膨胀性病变,伴有腮腺、颞骨和颅内延伸。活检提示为大 B 细胞淋巴瘤。化疗 2 年后,患者病情好转。

结论

淋巴瘤是头颈部肿瘤的第二大常见类型,仅次于表皮样癌。下颌骨的发病率仅为 0.6%,几乎均为 B 细胞淋巴瘤。它们常被误诊为牙科病变。化疗后 1 年完全缓解率为 60%至 80%。

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