Sauer H, Ambrosius H, Behn I, Fiebig H, Köllner B, Leykun J, Schubert S, Spannemann B
Abteilung für Tropenmedizin und klinische Parasitologie, Karl-Marx-Universität Leipzig.
Allerg Immunol (Leipz). 1990;36(4):333-41.
Sera from 251 children living in endemic areas (Schistosoma mansoni or Schistosoma haematobium) and from 188 hospital outpatients in Ethiopia were evaluated for specific IgG4 antibodies reacting with Schistosoma mansoni adult worm antigen employing an enzyme-immunoassay. Patients with schistosomiasis (n = 140) possessed a significantly higher mean value of specific IgG4 antibodies than normal controls (n = 30) and individuals from different countries who had no schistosomiasis but are infected with other parasites (n = 114). Blood samples dried on filter paper were also acceptable in these test. The use of the test in diagnosis is compared and assessed with parasitological methods.
采用酶免疫测定法，对生活在血吸虫病流行区（曼氏血吸虫或埃及血吸虫）的251名儿童以及埃塞俄比亚188名医院门诊患者的血清进行检测，以评估与曼氏血吸虫成虫抗原发生反应的特异性IgG4抗体。血吸虫病患者（n = 140）的特异性IgG4抗体平均水平显著高于正常对照组（n = 30）以及来自不同国家、未感染血吸虫病但感染其他寄生虫的个体（n = 114）。在这些检测中，滤纸干燥血样也是可行的。该检测方法在诊断中的应用与寄生虫学方法进行了比较和评估。
