Wachtel H C, Bernimoulin J P, Lekovic V M
Polikliniken für ZMK Nord, Freie Universität Berlin.
Parodontol. 1990;1(1):69-84.
The implantation of alloplastic materials in infrabony defects is controversely discussed. Only calcium phosphate ceramics have been proven as implantation materials for clinical use. All of the materials not being inert they undergo biodegradation. The extent of biodegradation is most pronounced with tricalciumphosphate (TCP). It had been shown in clinical studies that reduction of probing depth and gain of probing attachment level increased with implantation when compared to surgery only. Formation of new attachment however, can only be verified by histological analysis. Block sections of human teeth demonstrated different results in terms of gain of attachment when porous hydroxyapatite (HA) was implanted. Histometric analysis of a study in dogs showed significant gain of attachment by implanting porous HA and TCP in infrabony defects. Using solid HA or a modified Widman flap healing occurred only by reparation forming a long junctional epithelium. In conclusion, it can be stated that regeneration of periodontal tissues may be achieved by means of implantation of porous HA and TCP. However, long term results are not available and the clinical parameters to obtain predictable results still have to be defined.
关于在骨下缺损中植入异体材料一直存在争议。只有磷酸钙陶瓷已被证明可作为临床使用的植入材料。所有这些材料都不是惰性的,它们会发生生物降解。生物降解程度在磷酸三钙(TCP)中最为明显。临床研究表明,与仅进行手术相比,植入时探诊深度的减少和探诊附着水平的增加更为明显。然而,新附着的形成只能通过组织学分析来证实。当植入多孔羟基磷灰石(HA)时,人类牙齿的块状切片在附着增加方面显示出不同的结果。一项对狗的研究的组织计量分析表明,在骨下缺损中植入多孔HA和TCP可显著增加附着。使用固体HA或改良的Widman瓣时,愈合仅通过形成长结合上皮的修复来实现。总之,可以说通过植入多孔HA和TCP可以实现牙周组织的再生。然而,尚无长期结果,获得可预测结果的临床参数仍有待确定。