Department of Internal Medicine, University at Buffalo, New York, USA.
Am J Med Sci. 2011 Feb;341(2):157-9. doi: 10.1097/MAJ.0b013e3181f99cc7.
Endocarditis caused by Abiotrophia accounts for 5% of all cases of infective endocarditis (Roberts et al, Rev Infect Dis. 1979;1:955-66) and 5% to 6% of all cases of streptococcal endocarditis (Bouvet, Eur Heart J. 1995;16(suppl B):24-7; Brouqui et al, Clin Microbiol Rev. 2001;14:177-207). This endocarditis is associated with a high rate of embolization and treatment failure (Bouvet, Eur Heart J. 1995;16(suppl B):24-7). Neurological complications occur in 20% to 40% of all cases of infective endocarditis (Ossorio et al, Hosp Physician. 2003;39:21-4). Subarachnoid hemorrhage is a rare but devastating neurological complication. The authors presented a case of massive fatal subarachnoid hemorrhage in a patient with Abiotrophia defectiva endocarditis. To our knowledge, there are only 2 reported cases of mycotic aneurysms in Abiotrophia endocarditis, 1 of which was associated with subarachnoid hemorrhage (Leonard et al, N Engl J Med. 2001;344:233-4; Yang et al, Am J Med Sci. 2010;339:190-1).
阿比奥特罗非亚引起的心内膜炎占感染性心内膜炎总病例的 5%（Roberts 等人，Rev Infect Dis. 1979;1:955-66）和链球菌性心内膜炎总病例的 5%到 6%（Bouvet，Eur Heart J. 1995;16(suppl B):24-7；Brouqui 等人，Clin Microbiol Rev. 2001;14:177-207）。这种心内膜炎与栓塞和治疗失败的发生率较高相关（Bouvet，Eur Heart J. 1995;16(suppl B):24-7）。感染性心内膜炎总病例中有 20%到 40%会出现神经并发症（Ossorio 等人，Hosp Physician. 2003;39:21-4）。蛛网膜下腔出血是一种罕见但具有破坏性的神经并发症。作者报告了一例因阿比奥特罗非亚缺陷性心内膜炎导致的大量致命性蛛网膜下腔出血病例。据我们所知，阿比奥特罗非亚心内膜炎中仅有 2 例报道的真菌性动脉瘤病例，其中 1 例与蛛网膜下腔出血相关（Leonard 等人，N Engl J Med. 2001;344:233-4；Yang 等人，Am J Med Sci. 2010;339:190-1）。
