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前民主德国牛深部皮肤癣菌病的系统防治

Systematic control of dermatophytosis profunda of cattle in the former GDR.

作者信息

Kielstein P

机构信息

Research Institute for Bacterial Animal Diseases, Jena-Zwätzen, Germany.

出版信息

Mycoses. 1990 Nov-Dec;33(11-12):575-9. doi: 10.1111/myc.1990.33.11-12.575.

DOI:10.1111/myc.1990.33.11-12.575
PMID:2103596
Abstract

Human occupational diseases orginated from Trichophyton verrucosum infection of cattle belonged to the most frequent zooanthroponoses since 1960. Morbidity peaks of this human dermatophytosis could be observed in 1970 and 1971 with about 740 cases of occupational diseases per year. The ecological properties of Tr. verrucosum (compulsory monoxenic parasite), the pathogenetic development of bovine dermatophytosis (rising immunity with subsequent elimination of the agent), systematic medical therapy and prophylaxis with griseofulvin and other drugs as well as the application of Tr. verrucosum live vaccines were the preconditions for a successful control of this zooanthroponosis. Since then the number of human and animal diseases could be essentially reduced.

摘要

自1960年以来,由牛疣状毛癣菌感染引发的人类职业病属于最常见的人畜共患病。1970年和1971年观察到这种人类皮肤癣菌病的发病率高峰,每年约有740例职业病病例。疣状毛癣菌的生态学特性(专性单宿主寄生虫)、牛皮肤癣菌病的发病机制发展(免疫力增强随后病原体被清除)、使用灰黄霉素和其他药物进行系统药物治疗和预防以及应用疣状毛癣菌活疫苗是成功控制这种人畜共患病的前提条件。从那时起,人和动物疾病的数量得以大幅减少。

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Efficacy of a live attenuated Trichophyton verrucosum vaccine for control of bovine dermatophytosis.一种减毒活疣状毛癣菌疫苗对控制牛皮肤癣菌病的疗效。
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