Koroscil Thomas M, McDonald Stephen, Stutes Shahan, Vila Raul J
Division of Endocrinology, Boonshoft School of Medicine, Wright State University, Dayton, OH, USA.
South Med J. 2010 Dec;103(12):1238-42. doi: 10.1097/SMJ.0b013e3181eda0de.
A nine-weeks pregnant, 27-year-old female was admitted for hypertension with a blood pressure of 213/110 mm Hg, headaches, palpitations, and anxiety. There was no previous history of hypertension or pre-eclampsia. She had elevated urinary normetanephrine, plasma-free normetanephrine, and plasma-free metanephrine concentrations. Phenoxybenzamine and labetalol were initiated for presumed pheochromocytoma. At thirteen weeks of pregnancy, a noncontrast magnetic resonance imaging (MRI) of the abdomen failed to identify an adrenal or extra-adrenal mass. At 21-weeks gestation, an abdominal [18-F]-fluorodeoxyglucose positron emission tomography with computed tomography demonstrated an extra-adrenal lesion. The patient underwent a laparotomy during the second trimester with successful removal of a benign paraganglioma.
一名27岁、怀孕9周的女性因高血压入院,血压为213/110毫米汞柱,伴有头痛、心悸和焦虑。既往无高血压或先兆子痫病史。她的尿去甲肾上腺素、血浆游离去甲肾上腺素和血浆游离间甲肾上腺素浓度升高。因疑似嗜铬细胞瘤开始使用酚苄明和拉贝洛尔治疗。怀孕13周时,腹部非增强磁共振成像(MRI)未发现肾上腺或肾上腺外肿块。妊娠21周时,腹部[18-F]氟脱氧葡萄糖正电子发射断层扫描计算机断层扫描显示有一个肾上腺外病变。患者在孕中期接受了剖腹手术,成功切除了一个良性副神经节瘤。