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“内卷式”板层角膜移植术治疗累及周边角膜的角膜移植术后角膜扩张的眼表重建。

"Tuck in" lamellar keratoplasty for tectonic management of postkeratoplasty corneal ectasia with peripheral corneal involvement.

机构信息

Melbourne University Department of Ophthalmology, Centre for Eye Research Australia, University of Melbourne, Australia.

出版信息

Cornea. 2011 Feb;30(2):171-4. doi: 10.1097/ICO.0b013e3181ead943.

Abstract

PURPOSE

Evaluation of "tuck in" lamellar keratoplasty (TILK) for the surgical management of postkeratoplasty corneal ectasia with peripheral corneal involvement.

METHODS

Four eyes of 3 patients with post-penetrating keratoplasty corneal ectasia and contact lens intolerance underwent TILK that included a central lamellar keratoplasty with intrastromal tucking of the peripheral flange, at the Royal Victorian Eye and Ear Hospital, Melbourne, Australia. The main outcome measures analyzed were uncorrected visual acuity, best-corrected visual acuity, keratometry, and endothelial cell density.

RESULTS

The original indication for surgery was keratoconus in all the cases. TILK was successfully performed in these patients. Mean follow-up period was 13 months (SD: 7.74) (range: 6-24 months). The preoperative best-corrected visual acuity improved from a mean value of 0.05 (SD: 0.05) to 0.34 (SD: 0.03) (P < 0.001). Mean keratometry decreased from 59.67 diopter (SD: 7.18) preoperatively to 43.50 diopter (SD: 2.23) postoperatively (P < 0.005). Mean endothelial cell loss after TILK was 5.93% (SD: 3.06) (P < 0.206). All grafts were clear at the last follow-up, and no cases of stromal or endothelial graft rejection were encountered.

CONCLUSIONS

TILK can be successfully performed for post-penetrating keratoplasty corneal ectasia with peripheral corneal thinning.

摘要

目的

评估“内卷式”板层角膜移植术(TILK)治疗伴有周边角膜受累的穿透性角膜移植术后角膜扩张的效果。

方法

在澳大利亚墨尔本皇家维多利亚眼耳医院,对 3 例穿透性角膜移植术后角膜扩张伴接触镜不耐受的患者的 4 只眼行 TILK 治疗,该手术包括中央板层角膜移植术,周边边缘行基质内内卷。主要观察指标为未矫正视力、最佳矫正视力、角膜曲率计和角膜内皮细胞密度。

结果

所有病例的最初手术指征均为圆锥角膜。这些患者均成功完成了 TILK。平均随访时间为 13 个月(标准差:7.74)(范围:6-24 个月)。术前最佳矫正视力从平均 0.05(标准差:0.05)提高至 0.34(标准差:0.03)(P<0.001)。术前平均角膜曲率计从 59.67 屈光度(标准差:7.18)下降至术后的 43.50 屈光度(标准差:2.23)(P<0.005)。TILK 后平均内皮细胞丢失 5.93%(标准差:3.06)(P<0.206)。末次随访时所有移植物均透明,未发生任何基质或内皮移植物排斥反应。

结论

TILK 可成功治疗伴有周边角膜变薄的穿透性角膜移植术后角膜扩张。

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