Walker Karen
Thomson Reuters, 77 Hatton Garden, London, EC1N 8JS, UK.
IDrugs. 2010 Nov;13(11):746-8.
The 50th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), held in Boston, included topics covering new therapeutic developments in the field of infectious disease. This conference report highlights selected presentations on research with novel antimicrobial agents. Investigational drugs discussed include the chitin synthase inhibitor nikkomycin Z (Valley Fever Solutions/University of Arizona), the glycosylphosphatidylinositol biosynthesis inhibitor E-1210 (Eisai), the β-1,3-d-glucan synthesis inhibitor MK-3118 (Merck & Co/SCYNEXIS), the metalloenzyme inhibitors VT-1129 and VT-1161 (both Viamet Pharmaceuticals), and the anti-inflammatory nanoemulsion NB-003 (NanoBio).
第50届抗菌药物和化疗跨学科会议(ICAAC)在波士顿举行,会议主题涵盖传染病领域的新治疗进展。本会议报告重点介绍了关于新型抗菌药物研究的部分演讲内容。讨论的研究药物包括几丁质合酶抑制剂多氧霉素Z(山谷热解决方案公司/亚利桑那大学)、糖基磷脂酰肌醇生物合成抑制剂E-1210(卫材株式会社)、β-1,3-D-葡聚糖合成抑制剂MK-3118(默克公司/SCYNEXIS)、金属酶抑制剂VT-1129和VT-1161(均为Viamet制药公司)以及抗炎纳米乳剂NB-003(纳米生物公司)。