Uke Maya S, Kulkarni Manisha B, Ajit Dulhan, Gujral Sumeet
Division of Cytology, Department of Pathology, Tata Memorial Hospital, Dr. E Borges Marg, Parel, Mumbai, India.
Acta Cytol. 2010 Sep-Oct;54(5 Suppl):907-10.
Hidradenoma papilliferum is a rare benign tumor of the vulva that occurs mainly in women in the skin of the anogenital region. Clinically it may mimic a carcinoma, so the correct cytologic interpretation of the tumor cells with subsequent careful histologic confirmation is essential for good management.
A 44-year-old woman who had a history of hysterectomy 14 years earlier presented with a small, exophytic growth on the labia majora. Fine needle aspiration cytology and vulvar scraping of the lesion were reported as a malignant tumor, and the case was referred to our center for further management. Repeat vulvar smears showed mainly groups and clusters of benign-looking glandular cells and were interpreted as a benign tumor. Subsequent histology confirmed the diagnosis of hidradenoma papilliferum.
This case highlights the cytologic features of hidradenoma papilliferum on cytologic smears. The clinical presentation should not mislead the cytologic interpretation of the tumor cells.
乳头汗腺瘤是一种罕见的外阴良性肿瘤，主要发生于女性的肛门生殖器区域皮肤。临床上它可能类似癌，因此对肿瘤细胞进行正确的细胞学解释并随后进行仔细的组织学确认对于良好的治疗管理至关重要。
一名44岁女性，14年前有子宫切除史，现大阴唇出现一个小的外生性肿物。细针穿刺细胞学检查及病变处外阴刮片报告为恶性肿瘤，该病例被转诊至我们中心做进一步处理。重复的外阴涂片主要显示为外观良性的腺细胞团和簇，诊断为良性肿瘤。随后的组织学检查确诊为乳头汗腺瘤。
本病例突出了乳头汗腺瘤在细胞学涂片上的特征。临床表现不应误导对肿瘤细胞的细胞学解释。
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