微脉冲二极管激光小梁成形术——180 度治疗。

Micropulse diode laser trabeculoplasty -- 180-degree treatment.

机构信息

Department of Ophthalmology, Päijät-Häme Central Hospital, Lahti, Finland.

出版信息

Acta Ophthalmol. 2012 Aug;90(5):441-4. doi: 10.1111/j.1755-3768.2010.02026.x. Epub 2010 Nov 4.

DOI:10.1111/j.1755-3768.2010.02026.x

PMID:21054817

Abstract

PURPOSE

To evaluate the outcome of 180° micropulse diode laser trabeculoplasty (MDLT) in patients with open-angle glaucoma.

METHODS

A retrospective review of 40 eyes of 29 MDLT-treated patients with a minimum follow-up time of 6 months. Successful outcome was defined as follows: (i) a ≥20% or (ii) a ≥3-mmHg decrease of intraocular pressure (IOP), no further need for laser- or incisional surgery and the number of glaucoma medication was the same or less than preoperative. These definitions will from now on be referred to as definition one and definition two.

RESULTS

Life-table analysis showed an overall success rate of 2.5% (1/40) and 7.5% (3/40) (according to definitions one and two, respectively) after up to 19 months of follow-up. The average time for failure was by definition one 2.9 months (standard deviation, SD ± 3.5, range 1-12 months) and by definition two 3.3 months (SD ± 3.9, range 1-16 months). There were no intra- or postoperative complications caused by MDLT. Postoperative inflammatory reaction, cells and flare, was scanty.

CONCLUSION

Our results suggest that 180° MDLT is a safe but ineffective treatment in patients with open-angle glaucoma.

摘要

目的

评估 180°微脉冲二极管激光小梁成形术（MDLT）治疗开角型青光眼的疗效。

方法

回顾性分析了 29 例 40 只眼接受 MDLT 治疗的患者，随访时间至少为 6 个月。成功的结果定义如下：（i）眼压（IOP）降低≥20%或（ii）降低≥3mmHg，无需进一步进行激光或手术治疗，且青光眼药物的使用数量与术前相同或更少。这些定义将被称为定义一和定义二。

结果

寿命表分析显示，在长达 19 个月的随访中，总体成功率分别为 2.5%（1/40）和 7.5%（3/40）（根据定义一和二）。根据定义一，失败的平均时间为 2.9 个月（标准差±3.5，范围 1-12 个月），根据定义二为 3.3 个月（标准差±3.9，范围 1-16 个月）。MDLT 没有引起术中或术后并发症。术后炎症反应、细胞和闪光均较少。