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[单焦点与多焦点非球面人工晶状体植入患者视觉质量的临床观察]

[Clinical observation on visual quality in patients implanted with monofocal and multifocal aspheric intraocular lenses].

作者信息

Wang Wen-ying, Wang Jun, Zhang Jing, Zhao Shi-qiang, Ma Jian-xin

机构信息

Beijing Tongren Eye Center, Tongren Hospital Capital Medical University, Beijing Ophthalmic & Visual Sciences Key Lab, Beijing 100730, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2010 Aug;46(8):686-90.

Abstract

OBJECTIVE

To evaluate the visual quality in patients implanted with aspheric diffractive multifocal intraocular lens.

METHODS

Prospective nonrandomized controlled study. One hundred cataract eyes in 50 patients were included. Patients received AcrySof IQ ReSTOR IOL (SN6AD3) or AcrySof IQ IOL (SN60WF) implantation. The follow up period was 6 months. The mean of uncorrected distance visual acuity (UCDVA), best corrected distance visual acuity (BCDVA), uncorrected near visual acuity (UCNVA), best distance-corrected near visual acuity (BCNVA) and intermediate uncorrected visual acuity in patients with SN6AD3 and SN60WF was compared preoperatively and postoperatively in all patients. Photopic and mesopic contrast sensitivity function with and without glare were tested at 6 months after operation. Aberrations were recorded postoperatively. Subjective outcomes were assessed by VF-14 questionnaire. The chi-square test was applied to compare categorical variables and the paired-samples t test was used to compare the measure data.

RESULTS

Postoperatively, there were no significant differences between groups in spherical equivalent (SE) (t = 0.233, P = 0.876), UCDVA (t = 1.018, P = 0.265) or BCNVA (t = 0.679, P = 0.501). The BCDVA in the monofocal IOL group was better than that in the multifocal IOL group (t = 2.388, P = 0.021). UCNVA improved remarkably after the implantation of multifocal IOL (t = 11.311, P = 0.000). The intermediate UCVA in the monofocal IOL eyes was butter than that in the multifocal IOL at 60 cm (t = 2.414, P = 0.020). The total aberration (F = 5.169, P = 0.041), total low grade (F = 4.973, P = 0.036) and total high grade total aberrations (F = 4.640, P = 0.048) were higher in the multifocal IOL group. There was no difference between these two groups in the defocus (F = 0.862, P = 0.358), astigmatism (F = 3.893, P = 0.052), spherical aberration (F = 1.743, P = 0.055), coma (F = 2.724, P = 0.105) and trefoil (F = 3.014, P = 0.109). Contrast sensitivity in eyes with multifocal IOL was lower than that in eyes with monofocal IOL, especially under mesopic conditions without glare at 6 c/d (t = 2.16, P = 0.041) at 3 c/d (t = 2.329, P = 0.029) and 6 c/d under mesopic conditions with glare (t = 2.087, P = 0.048). Most patients were satisfied with their IOL implantation. Percentage of patients wearing spectacle for distance vision were less than 4% in all groups. Percentage in patients wearing spectacle for near vision in SN60WF and SN6AD3 groups was 60% and 16%, respectively. Percentage of overall spectacle wear was 64% and 24% in patients wearing SN60WF and SN6AD3, respectively. On the questionnaire, patients in multifocal IOL group complained with double vision, trouble in night vision and halo; while patients in monofocal IOL group noted more about near blur.

CONCLUSION

Compared with monofocal lenses, multifocal IOL provide greater depth of focus so that better near vision, higher percentage of spectacle independence and satisfactory visual function, are obtained but the contrast sensitivity decreases slightly.

摘要

目的

评估植入非球面衍射多焦点人工晶状体患者的视觉质量。

方法

前瞻性非随机对照研究。纳入50例患者的100只白内障眼。患者接受AcrySof IQ ReSTOR人工晶状体(SN6AD3)或AcrySof IQ人工晶状体(SN60WF)植入。随访期为6个月。比较所有患者术前和术后SN6AD3组和SN60WF组患者的未矫正远视力(UCDVA)、最佳矫正远视力(BCDVA)、未矫正近视力(UCNVA)、最佳矫正近视力(BCNVA)及中间距离未矫正视力的平均值。术后6个月测试有眩光和无眩光情况下的明视觉和 mesopic 对比敏感度函数。术后记录像差。通过VF - 14问卷评估主观结果。应用卡方检验比较分类变量,配对样本t检验用于比较计量资料。

结果

术后,两组在等效球镜度(SE)(t = 0.233,P = 0.876)、UCDVA(t = 1.018,P = 0.265)或BCNVA(t = 0.679,P = 0.501)方面无显著差异。单焦点人工晶状体组的BCDVA优于多焦点人工晶状体组(t = 2.388,P = 0.021)。植入多焦点人工晶状体后UCNVA显著改善(t = 11.311,P = 0.000)。单焦点人工晶状体眼在60 cm处的中间UCVA优于多焦点人工晶状体眼(t = 2.414,P = 0.020)。多焦点人工晶状体组的总像差(F = 5.169,P = 0.041)、总低阶像差(F = 4.973,P = 0.036)和总高阶像差(F = 4.640,P = 0.048)更高。两组在散焦(F = 0.862,P = 0.358)、散光(F = 3.893,P = 0.052)、球差(F = 1.743,P = 0.055)、彗差(F = 2.724,P = 0.105)和三叶草像差(F = 3.014,P = 0.109)方面无差异。多焦点人工晶状体眼的对比敏感度低于单焦点人工晶状体眼,尤其是在mesopic条件下无眩光时6 c/d(t = 2.16,P = 0.041)、3 c/d(t = 2.329,P = 0.029)以及mesopic条件下有眩光时6 c/d(t = 2.087,P = 0.048)。大多数患者对人工晶状体植入满意。所有组中远距离视力佩戴眼镜的患者百分比均小于4%。SN60WF组和SN6AD3组中近距离视力佩戴眼镜的患者百分比分别为60%和16%。佩戴SN60WF和SN6AD3的患者总体佩戴眼镜百分比分别为64%和24%。在问卷中,多焦点人工晶状体组患者抱怨有复视、夜间视力问题和光晕;而单焦点人工晶状体组患者更多提到近距离模糊。

结论

与单焦点晶状体相比,多焦点人工晶状体提供了更大的焦深,从而获得了更好的近视力、更高的眼镜独立率和令人满意的视觉功能,但对比敏感度略有下降。

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