Schnitzer Jay, Ozuzu Yvonne
Department of Podiatric Surgery, Aria Health Hospital, Langhorne, PA 19114, USA.
J Foot Ankle Surg. 2011 Jan-Feb;50(1):77-81. doi: 10.1053/j.jfas.2010.07.009. Epub 2010 Nov 4.
The authors present a case of spitzoid nevus of the left fourth toe in a 16-year-old boy, which was confirmed by biopsy to be a Spitz nevus. In a young individual, we feel that it is important to maintain a high index of suspicion for an atypical lesion that displays unusual physical findings. Spitz nevus is an infrequent, acquired melanocytic nevus composed of epithelial and spindle melanocytes that is difficult to differentiate from a melanoma. Presently, there are no immunohistochemical markers or molecular biologic techniques that can be used to make a completely certain diagnosis of Spitz nevus versus melanoma. Spitz tumors are most commonly located on the lower extremities in children. Treatment of the lesion is typically carried out by means of excision.
作者报告了一例16岁男孩左足第四趾的梭形细胞痣病例，活检证实为Spitz痣。对于年轻个体中表现出异常体征的非典型病变，我们认为保持高度怀疑指数很重要。Spitz痣是一种罕见的后天性黑素细胞痣，由上皮样和梭形黑素细胞组成，很难与黑色素瘤区分开来。目前，尚无免疫组化标志物或分子生物学技术可用于完全确诊Spitz痣与黑色素瘤。Spitz肿瘤最常见于儿童的下肢。该病变的治疗通常通过切除进行。
