Lee Anson M, Clark Kal, Bailey Marci S, Aziz Abdulhameed, Schuessler Richard B, Damiano Ralph J
Division of Cardiothoracic Surgery, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, St. Louis, MO 63110, USA.
Innovations (Phila). 2010 Jul-Aug;5(4):281-6. doi: 10.1097/IMI.0b013e3181ee3815.
The Cox-Maze procedure (CMP) for the surgical treatment of atrial fibrillation (AF) traditionally has required a median sternotomy and cardiopulmonary bypass. This study describes a method using ablation technologies to create the full Cox-Maze lesion set through a 5- to 6-cm right minithoracotomy.
Twenty-two consecutive patients underwent a CMP through a right mini-thoracotomy and cardiopulmonary bypass. All patients were followed prospectively with electrocardiogram and 24-hour Holter monitoring at 3, 6, and 12 months. The CMP lesion set was created using bipolar radiofrequency energy and cryotherapy.
There was no operative mortality or major complications.Two patients required a permanent pacemaker. Five patients (23%) had early atrial tachyarrhythmias. At last follow-up(mean, 18 ± 12 months), all the patients (n=22) were free from atrial dysrhythmias. At 3 months (n=19), 84% of patients were off antiarrhythmic drugs. At 6 months (n=18), 94% of patients were free from AF and off antiarrhythmic medications. At 12 months (n=16), 81% of patients were free from AF and off antiarrhythmic drugs and three patients remained on warfarin for a mechanical mitral valve.
A full CMP can be performed through a right mini-thoracotomy with outstanding short-term results. This less invasive procedure can be offered to patients without compromising efficacy.
传统上,用于治疗心房颤动(AF)的Cox迷宫手术(CMP)需要正中胸骨切开术和体外循环。本研究描述了一种通过5至6厘米的右胸小切口使用消融技术创建完整Cox迷宫损伤组的方法。
连续22例患者通过右胸小切口和体外循环接受CMP。所有患者在3、6和12个月时接受前瞻性心电图和24小时动态心电图监测。使用双极射频能量和冷冻疗法创建CMP损伤组。
无手术死亡或重大并发症。两名患者需要永久起搏器。五名患者(23%)出现早期房性快速心律失常。在最后一次随访时(平均18±12个月),所有患者(n = 22)均无房性心律失常。在3个月时(n = 19),84%的患者停用抗心律失常药物。在6个月时(n = 18),94%的患者无房颤且停用抗心律失常药物。在12个月时(n = 16),81%的患者无房颤且停用抗心律失常药物,三名患者因机械二尖瓣置换仍服用华法林。
完整的CMP可通过右胸小切口进行,短期效果优异。这种侵入性较小的手术可以提供给患者,而不影响疗效。