Sato K, Kayama T, Sakurai Y, Ogawa A, Wada T
Department of Neurosurgery, Tohoku University School of Medicine.
No Shinkei Geka. 1990 Jan;18(1):63-6.
A rare case of recurrence of a metastatic brain tumor which disappeared due to chemotherapy only is reported. A 52-year-old male was noticed to have an abnormal shadow in his chest X-P at a routine medical examination, so a close examination was made. He was diagnosed as having right renal cell carcinoma which had metastasized to the lung. He was treated by intra-arterial infusion of anti-cancer drugs and embolization of the right renal artery. No renal symptom was seen, growth of the primary tumor stopped, and the abnormal shadow in his chest diminished. However, weakness in the left hand appeared 19 months after the first examination and he was admitted to our clinic. He was alert, but slight left hand weakness was observed. CT scan revealed a diffusely enhanced mass in the right parietal lobe. Total removal of the brain tumor was performed and the histology was metastasis of renal cell carcinoma. He was discharged and was able to walk but he had slight left hemiparesis. UFT 6 capsules a day were administrated in our out-patient clinic. However, CT scan revealed recurrence of the tumor 2 weeks after discharge, we followed up with conservative treatment, and no growth of the tumor was seen. It disappeared 5 months after discharge after being treated with UFT only. We regard UFT as having been effective in this case.
报告了一例罕见的转移性脑肿瘤复发病例,该肿瘤仅通过化疗就消失了。一名52岁男性在常规体检时胸部X光发现异常阴影,因此进行了详细检查。他被诊断为右肾细胞癌已转移至肺部。他接受了动脉内抗癌药物灌注和右肾动脉栓塞治疗。未出现肾脏症状,原发肿瘤生长停止,胸部异常阴影缩小。然而,首次检查19个月后左手出现无力,他入住了我们的诊所。他神志清醒,但观察到左手轻微无力。CT扫描显示右顶叶有一个弥漫性强化肿块。对脑肿瘤进行了全切,组织学检查为肾细胞癌转移。他出院后能够行走,但有轻微左半身轻瘫。在我们的门诊每天给予优福定6粒胶囊。然而,出院2周后CT扫描显示肿瘤复发,我们采用保守治疗进行随访,未见肿瘤生长。仅用优福定治疗后,肿瘤在出院5个月后消失。我们认为优福定在该病例中有效。