CCN5：生物学与病理生理学。
CCN5: biology and pathophysiology.
出版信息
J Cell Commun Signal. 2010 Oct;4(3):119-30. doi: 10.1007/s12079-010-0098-7. Epub 2010 Sep 21.
Abstract
CCN5 is one of six proteins in the CCN family. This family of proteins has been shown to play important roles in many processes, including proliferation, migration, adhesion, extracellular matrix regulation, angiogenesis, tumorigenesis, fibrosis, and implantation. In this review, we focus on the biological and putative pathophysiological roles of CCN5. This intriguing protein is structurally unique among the CCN family members, and has a unique biological activity profile as well.
摘要
CCN5 是 CCN 家族中的六种蛋白之一。该蛋白家族在许多过程中发挥着重要作用，包括增殖、迁移、黏附、细胞外基质调节、血管生成、肿瘤发生、纤维化和植入。在这篇综述中，我们重点关注 CCN5 的生物学和推测的病理生理学作用。这种引人入胜的蛋白在 CCN 家族成员中结构独特，并且具有独特的生物学活性特征。
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