Jault F, Cabrol C, Gandjbakhch I, Pavie A, Bors V, Vaissier E, Cabrol A
Service de chirugie thoracique et cardio-vasculaire, hôpital de la Pitié, Paris.
Arch Mal Coeur Vaiss. 1990 Feb;83(2):205-8.
Between 1973 and 1987, 33 patients underwent pulmonary thromboendarterectomy for chronic pulmonary embolism. Twenty-six patients were in Class III of the NYHA Classification, 5 in Class IV with overt right ventricular failure and 2 in Class II. The average pO2 was 60 mmHg under basal conditions without oxygen therapy. The amputation of the pulmonary vascular tree was greater than 50 per cent in all patients. The average systolic pulmonary artery pressure was 70 mmHg. Twenty patients were operated by a lateral thoracotomy without CPB and 6 by sternotomy with CPB under normothermia with or without cardiac fibrillation. The later method avoids having to open the pleura and seemed to give better haemodynamic control. Interruption of the inferior vena cava was systematic in all cases. The global operative mortality was 20 per cent but this seemed to be less in the patients operated by sternotomy under normothermic CPB (no deaths in 6 patients). The authors consider that this technique should be studied in a larger series of patients. Eighteen patients are still being followed up; the clinical and scintigraphic and/or angiographic improvement is clearcut in the majority of cases.
1973年至1987年间,33例患者因慢性肺栓塞接受了肺动脉血栓内膜剥脱术。26例患者属于纽约心脏协会(NYHA)心功能分级III级,5例为IV级且有明显右心衰竭,2例为II级。在未进行氧疗的基础条件下,平均动脉血氧分压为60 mmHg。所有患者的肺血管树切除率均超过50%。平均肺动脉收缩压为70 mmHg。20例患者通过侧胸壁切口在非体外循环下进行手术,6例通过胸骨切开术在常温体外循环下进行手术,体外循环时有或无心脏颤动。后一种方法避免了打开胸膜,似乎能更好地控制血流动力学。所有病例均常规进行下腔静脉阻断。总体手术死亡率为20%,但在常温体外循环下通过胸骨切开术进行手术的患者中,死亡率似乎较低(6例患者无死亡)。作者认为,应在更多患者中研究该技术。18例患者仍在接受随访;大多数病例的临床、闪烁扫描和/或血管造影结果有明显改善。