Hielscher A H, Liu H, Chance B, Tittel F K, Jacques S L
Appl Opt. 1996 Feb 1;35(4):719-28. doi: 10.1364/AO.35.000719.
We present numerical and experimental results of time-resolved emission profiles from various layered turbid media. Numerical solutions determined by time-resolved Monte Carlo simulations are compared with measurements on layered-tissue phantoms made from gelatin. In particular, we show that in certain cases the effects of the upper layers can be eliminated. As a practical example, these results are used to analyze in vivo measurements on the human head. This demonstrates the influence of skin, skull, and meninges on the determination of the blood oxygenation in the brain.
我们展示了来自各种分层混浊介质的时间分辨发射剖面的数值和实验结果。通过时间分辨蒙特卡罗模拟确定的数值解与由明胶制成的分层组织模型的测量结果进行了比较。特别是,我们表明在某些情况下,上层的影响可以消除。作为一个实际例子,这些结果被用于分析人体头部的体内测量。这证明了皮肤、颅骨和脑膜对大脑血液氧合测定的影响。