促卵泡生成素（FSH）在正常、良性及恶性人类前列腺组织中的免疫细胞化学定位

Hurkadli K S, Sheth A R, Garde S V, Doctor V M, Sheth N A

Institute for Research in Reproduction ICMR, Bombay, India.

Br J Cancer. 1990 Feb;61(2):225-9. doi: 10.1038/bjc.1990.42.

Immunocytochemical localisation of follicle stimulating hormone (FSH) was carried out in normal, benign and malignant human prostates by indirect immunoperoxidase technique. Positive staining was observed in the epithelial cells of all the three categories, while the stromal cells showed a weakly positive reaction in a few specimens. The brown reaction product was dispersed in the cytoplasm of the epithelial cells. These observations demonstrate the presence of immunoreactive FSH-like peptide in human prostate. The significance of FSH in the aetiopathology of prostatic disorders is discussed.

采用间接免疫过氧化物酶技术对正常、良性及恶性人类前列腺组织进行促卵泡激素（FSH）的免疫细胞化学定位。在所有这三类组织的上皮细胞中均观察到阳性染色，而在少数标本的基质细胞中显示弱阳性反应。棕色反应产物分散在上皮细胞的细胞质中。这些观察结果表明人类前列腺中存在免疫反应性FSH样肽。文中讨论了FSH在前列腺疾病病因病理学中的意义。