Horowitz B L, Chari M V, James R, Bryan R N
Department of Radiology, Methodist Hospital, Baylor College of Medicine, Houston, TX 77030.
AJNR Am J Neuroradiol. 1990 Mar-Apr;11(2):299-302.
We analyzed the MR findings of five patients with benign intracranial epithelial tumors, commonly called epidermoids. The neoplasms were categorized into two groups on the basis of T1-weighted MR signal intensity (relative to brain): high-signal-intensity masses (short T1) and low-signal-intensity masses (long T1). Surgical specimens were obtained and analyzed by means of 13C MR spectroscopy. Epidermoids with short T1 values (white epidermoids) had a high lipid content comprising mixed triglycerides containing unsaturated fatty acid residues. Epidermoids with long T1 values (black epidermoids) exhibited a much reduced lipid content with no triglycerides or fatty acids. There was evidence of trace amounts of cholesterol in the black epidermoids. Our data indicate that epidermoids are a heterogeneous group of neoplasms that behave differently with T1-weighted MR imaging and 13C MR spectroscopy. The combination of MR imaging and spectroscopy holds the potential of further elucidating the nature of epidermoids as well as of other forms of neoplasms.
我们分析了5例颅内良性上皮性肿瘤（通常称为表皮样囊肿）患者的磁共振成像（MR）表现。根据T1加权MR信号强度（相对于脑），将这些肿瘤分为两组：高信号强度肿块（短T1）和低信号强度肿块（长T1）。获取手术标本并通过13C磁共振波谱进行分析。T1值短的表皮样囊肿（白色表皮样囊肿）脂质含量高，包含含有不饱和脂肪酸残基的混合甘油三酯。T1值长的表皮样囊肿（黑色表皮样囊肿）脂质含量大大降低，没有甘油三酯或脂肪酸。有证据表明黑色表皮样囊肿中有微量胆固醇。我们的数据表明，表皮样囊肿是一组异质性肿瘤，在T1加权MR成像和13C磁共振波谱中表现不同。MR成像和波谱学的结合有可能进一步阐明表皮样囊肿以及其他形式肿瘤的性质。
