成年马间充质基质细胞的脂肪生成分化

Adipogenic differentiation of adult equine mesenchymal stromal cells.

作者信息

Vidal Martin A, Lopez Mandi J

机构信息

JD Wheat Veterinary Orthopedic Research Laboratory, School of Veterinary Medicine, University of California - Davis, Davis, CA, USA.

出版信息

Methods Mol Biol. 2011;702:61-75. doi: 10.1007/978-1-61737-960-4_6.

DOI:10.1007/978-1-61737-960-4_6

PMID:21082395

Abstract

Equine adipose tissue-derived mesenchymal stem cells (ASCs) have only recently been investigated for their adipogenic, chondrogenic, and osteogenic differentiation potential. This chapter will briefly outline the molecular mechanisms leading to adipogenesis and the methods of equine adipose tissue harvest, ASC isolation, and adipogenic differentiation. The reader is also directed to other reported methods of adipogenesis for ASCs and mesenchymal stem cells (MSCs) from other tissues.

摘要

马脂肪组织来源的间充质干细胞（ASCs）直到最近才被研究其成脂、成软骨和成骨分化潜能。本章将简要概述导致脂肪生成的分子机制以及马脂肪组织采集、ASC分离和成脂分化的方法。读者还可参考其他已报道的关于ASCs以及来自其他组织的间充质干细胞（MSCs）的脂肪生成方法。