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蝶骨嵴内侧脑膜瘤:经额颞眶颧入路切除的早期和长期结果。

Medial sphenoid ridge meningiomas: early and long-term results of surgical removal using the fronto-temporo-orbito-zygomatic approach.

机构信息

Katedra i Oddzial Kliniczny Neurochirurgii, Slaski Uniwersytet Medyczny, Sosnowiec.

出版信息

Neurol Neurochir Pol. 2010 Sep-Oct;44(5):464-74. doi: 10.1016/s0028-3843(14)60137-7.

Abstract

BACKGROUND AND PURPOSE

The fronto-temporo-orbito-zygomatic approach (FTOZA) is an alternative to the pte-rional approach in surgical resection of meningiomas of the medial part of the lesser wing of the sphenoid bone. The purpose of this study is to present our results of treatment of these meningiomas using the FTOZA.

MATERIAL AND METHODS

Thirty patients (19 women, 11 men) with a central skull base tumour were included in the study. The neurological status of the patients was assessed before and after surgery as well as at the conclusion of treatment. The approximate volume of the operated tumour, its relation to large blood vessels, cranial nerves and brainstem, as well as consistency and vascularisation were assessed.

RESULTS

The symptom duration ranged from 1 to 36 months (median: 6 months). Impaired visual acuity was the predominant symptom in 27.5% of patients. Less frequent symptoms included paresis/paralysis of the third cranial nerve, headache, psychoorganic syndrome and epilepsy. Approximate volume of the tumours ranged from 5 to 212 mL (median: 63 mL). Total or subtotal resection was achieved in 77% of patients. The postoperative performance status improved in 16.5%, did not change in 52.8% and deteriorated in 26.4% of patients. One (3.3%) patient died after the surgery.

CONCLUSION

The FTOZA is a useful technique for removal of tumours expanding superiorly to the middle cranial fossa base without significant compression of the brain. Ability to remove tumours through the described approach decreases as the degree of infiltration of the clivus increases.

摘要

背景与目的

额颞眶颧入路(FTOZA)是蝶骨小翼内侧部脑膜瘤手术切除中翼点入路的一种替代方法。本研究旨在介绍使用 FTOZA 治疗这些脑膜瘤的结果。

材料与方法

研究纳入了 30 名(19 名女性,11 名男性)患有颅底中央肿瘤的患者。在手术前后以及治疗结束时评估患者的神经状态。评估了手术肿瘤的大致体积、其与大血管、颅神经和脑干的关系以及一致性和血管化程度。

结果

症状持续时间从 1 至 36 个月不等(中位数:6 个月)。视力障碍是 27.5%患者的主要症状。较少见的症状包括第三颅神经麻痹/瘫痪、头痛、精神器质性综合征和癫痫。肿瘤的大致体积从 5 至 212 毫升不等(中位数:63 毫升)。77%的患者实现了全切除或次全切除。术后表现状态改善的患者占 16.5%,无变化的占 52.8%,恶化的占 26.4%。1 名(3.3%)患者在手术后死亡。

结论

FTOZA 是一种有用的技术,可用于切除向上扩展至中颅窝基底而不显著压迫大脑的肿瘤。通过描述的方法切除肿瘤的能力随着斜坡浸润程度的增加而降低。

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