Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
J Eval Clin Pract. 2011 Aug;17(4):597-605. doi: 10.1111/j.1365-2753.2010.01562.x. Epub 2010 Nov 18.
Evidence-based medicine (EBM) is commonly advocated as a 'gold standard' of clinical practice. A prominent definition of EBM is: the integration of best research evidence with clinical expertise and patient values. Over time, various versions of a conceptual model or framework for implementing EBM (i.e. how to practice EBM) have been developed.
This paper (i) traces the evolution of the different versions of the conceptual model; (ii) tries to make explicit the underlying goals, assumptions and logic of the various versions by exploring the definitions and meaning of the components identified in each model, and the methods suggested for integrating these into clinical practice; and (iii) offers an analytic critique of the various model iterations.
A literature review was undertaken to identify, summarize, and compare the content of articles and books discussing EBM as a conceptual model to guide physicians in clinical practice.
Our findings suggest that the EBM model of clinical practice, as it has evolved over time, is largely belief-based, because it is lacking in empirical evidence and theoretical support. The model is not well developed and articulated in terms of defining model components, justifying their inclusion and suggesting ways to integrate these in clinical practice.
These findings are significant because without a model that clearly defines what constitutes an EBM approach to clinical practice we cannot (i) consistently teach clinicians how to do it and (ii) evaluate whether it is being done.
循证医学(EBM)通常被推崇为临床实践的“金标准”。EBM 的一个突出定义是:将最佳研究证据与临床专业知识和患者价值观相结合。随着时间的推移,已经开发出各种实施 EBM(即如何实践 EBM)的概念模型或框架的版本。
本文(i)追溯不同版本的概念模型的演变;(ii)通过探索每个模型中确定的组件的定义和含义,以及将这些组件整合到临床实践中的建议方法,试图明确各种版本的潜在目标、假设和逻辑;(iii)对各种模型迭代进行分析批判。
进行了文献回顾,以确定、总结和比较讨论 EBM 作为指导医生临床实践的概念模型的文章和书籍的内容。
我们的研究结果表明,随着时间的推移,临床实践中的 EBM 模型在很大程度上是基于信仰的,因为它缺乏经验证据和理论支持。该模型在定义模型组件、证明其包含的合理性以及提出将这些组件整合到临床实践中的方法方面还不够完善和明确。
这些发现意义重大,因为如果没有一个明确定义构成 EBM 临床实践方法的模型,我们就不能(i)一致地教导临床医生如何进行,以及(ii)评估是否正在进行。