De Weerdt S, Haentjens P, Van Binst A M, Baron I, Clement P, Vincken W
Department of Pneumology, Center for Outcomes Research and Laboratory for Experimental Surgery, Universitair Ziekenhuis Brussel (UZB), Brussels, Belgium.
B-ENT. 2010;6(3):171-5.
Both nasal continuous positive airway pressure (nCPAP) therapy and nose blowing can generate high pressures in the nose and sinuses. Nose blowing generates higher pressures than nCPAP therapy, but the duration of nCPAP therapy is considerably longer than the duration of nose blowing. Therefore, nCPAP could cause bone deformation. The aim of this study was to document the influence of the pressure generated by nCPAP therapy on the structure and dimensions of the sinuses and on the nose-blowing patterns of the patients.
The study included nine patients, who had recently been diagnosed with obstructive sleep apnea syndrome (OSAS) and had not received any previous treatment for OSAS. Before nCPAP therapy was started, they all underwent computer tomography (CT) in the prone position with sequential coronal slices followed by pressure measurements during nose blowing. After the initial measurements, nCPAP therapy commenced. All of the patients were treated with a fixed-pressure device and nasal mask for 6 mo. nCPAP therapy compliance was checked after 6 mo. At the end of the 6 mo treatment with nCPAP, coronal CT scans of the sinuses and pressure measurements during nose blowing were repeated.
Although CPAP therapy provides continuous positive pressure for several hours at night, bone structure and sinus dimensions appeared to be unchanged after 6 mo of therapy. However, CPAP therapy seemed to have an effect on the nose-blowing pattern of the patients, with a significant decrease in nose blowing pressure after 6 mo of CPAP treatment.
鼻持续气道正压通气(nCPAP)治疗和擤鼻均可在鼻腔和鼻窦内产生高压。擤鼻产生的压力高于nCPAP治疗,但nCPAP治疗的持续时间远长于擤鼻的持续时间。因此,nCPAP可能导致骨骼变形。本研究的目的是记录nCPAP治疗产生的压力对鼻窦结构和尺寸以及患者擤鼻模式的影响。
该研究纳入了9例最近被诊断为阻塞性睡眠呼吸暂停综合征(OSAS)且此前未接受过OSAS治疗的患者。在开始nCPAP治疗前,他们均在俯卧位接受计算机断层扫描(CT),扫描采用连续冠状位切片,随后进行擤鼻时的压力测量。初始测量后,开始nCPAP治疗。所有患者均使用固定压力设备和鼻面罩治疗6个月。6个月后检查nCPAP治疗的依从性。在nCPAP治疗6个月结束时,重复进行鼻窦冠状位CT扫描和擤鼻时的压力测量。
尽管CPAP治疗在夜间持续数小时提供正压,但治疗6个月后骨结构和鼻窦尺寸似乎未发生变化。然而,CPAP治疗似乎对患者的擤鼻模式有影响,CPAP治疗6个月后擤鼻压力显著降低。