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腹腔镜全直肠系膜切除术治疗中低位直肠癌的长期疗效

Long-term outcome of laparoscopic total mesorectal excision for middle and low rectal cancer.

作者信息

Zheng Min-Hua, Feng Bo, Hu Chun-Yun, Lu Ai-Guo, Wang Ming-Liang, Li Jian-Wen, Hu Wei-Guo, Zang Lu, Mao Zhi-Hai, Dong Tao-Tao, Dong Feng, Cai Wei, Ma Jun-Jun, Zong Ya-Ping, Li Michael Ka Wah

机构信息

Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, No. 197 Ruijin er Road, Shanghai, China.

出版信息

Minim Invasive Ther Allied Technol. 2010 Dec;19(6):329-39. doi: 10.3109/13645706.2010.527771.

DOI:10.3109/13645706.2010.527771
PMID:21091067
Abstract

This study aimed to assess the feasibility and long-term outcome of laparoscopic total mesorectal excision for middle and lower rectal cancer. Retrospective assessment was performed on 612 patients with middle and low rectal cancer in the surgery department of our hospital. Three-hundred and three patients underwent laparoscopic total mesorectal excision (LTME), and 309 patients underwent open TME (OTME). All the data regarding patient details, operative variables and the short- and long-term outcomes were collected and compared. The sphincter-preserving rates of the two groups were similar. The conversion rate in LTME was 2.31% (seven cases). Fourteen cases (6.67%) of protective diverting stoma were fashioned in the LTME group compared with 57 cases (26.64%) in the OTME group. The postoperative morbidity was the same in these two groups, while the postoperative period until bowel movement and hospital discharge was shorter in the LTME group (P < 0.01). The median follow-up period was 34 (6-81) months for the LTME group and 36 (6-81) months for the OTME group. Local recurrence rates, the five-year disease-free survival rate and the five-year overall survival rate showed no difference between the two groups. Laparoscopic surgery is feasible and safe in patients with middle and lower rectal cancer and can provide favorable short-term and long-term outcomes.

摘要

本研究旨在评估腹腔镜全直肠系膜切除术治疗中低位直肠癌的可行性及长期疗效。对我院外科612例中低位直肠癌患者进行回顾性评估。303例患者接受了腹腔镜全直肠系膜切除术(LTME),309例患者接受了开放全直肠系膜切除术(OTME)。收集并比较了所有患者的详细资料、手术变量以及短期和长期疗效。两组的保肛率相似。LTME组的中转开腹率为2.31%(7例)。LTME组有14例(6.67%)患者行预防性造口,而OTME组有57例(26.64%)。两组术后发病率相同,但LTME组术后至排便和出院的时间较短(P<0.01)。LTME组的中位随访时间为34(6 - 81)个月,OTME组为36(6 - 81)个月。两组的局部复发率、五年无病生存率和五年总生存率无差异。腹腔镜手术治疗中低位直肠癌患者是可行且安全的,并且能提供良好的短期和长期疗效。

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