Department of Anesthesiology, Mount Sinai Medical Center, New York, New York 10029, USA.
Semin Thorac Cardiovasc Surg. 2010 Summer;22(2):140-4. doi: 10.1053/j.semtcvs.2010.09.007.
Vasoplegic syndrome (VS) is a recognized and relatively common complication of cardiopulmonary bypass (CPB), appearing with an incidence ranging between 5% and 25%. It is characterized by significant hypotension, high or normal cardiac outputs and low systemic vascular resistance (SVR), and increased requirements for fluids and vasopressors during or after CPB. Patients developing VS are at increased risk for death and other major complications following cardiac surgery. This review will focus on the pathophysiology and contemporary strategies of treating VS encountered after CPB.
血管麻痹综合征（VS）是体外循环（CPB）中一种公认且相对常见的并发症，其发生率在 5%至 25%之间。它的特点是显著低血压、高或正常心输出量和低全身血管阻力（SVR），并且在 CPB 期间或之后对液体和血管加压药的需求增加。发生 VS 的患者在心脏手术后死亡和其他重大并发症的风险增加。本综述将重点介绍 CPB 后遇到的 VS 的病理生理学和当代治疗策略。
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